Lugata John, Makower Laetitia, Rapheal Ashley, Mwidibo Yusuph, Mchome Bariki, Mremi Alex
Department of Obstetrics and Gynecology Kilimanjaro Christian Medical Centre Moshi Tanzania.
Faculty of Medicine Kilimanjaro Christian Medical University College Moshi Tanzania.
Clin Case Rep. 2024 Dec 7;12(12):e9713. doi: 10.1002/ccr3.9713. eCollection 2024 Dec.
Brenner tumors are rare ovarian neoplasms that are typically small and unilateral. Most cases are benign; less than 5% of all Brenner tumors are borderline or proliferative. Brenner tumors originate from the follicular epithelium and consist of ovarian transitional cells surrounded by fibrous tissue. Here we present a case of a 49-year-old premenopausal woman from Northern Tanzania. This patient presented to our facility with acute abdominal pain. She also reported abdominal distention which was first noticed 12 months prior to presentation. Magnetic resonance imaging (MRI) identified a 21 × 17 × 5 cm complex cyst with a thickened wall on the right ovary. The radiological findings were suggestive of an ovarian cystadenoma; multiple intramural and subserosal uterine leiomyomas were also noted. A total abdominal hysterectomy (TAH) and bilateral salpingo-oophorectomy (BSO) was performed. Histopathological findings identified an atypical proliferative borderline Brenner tumor of the right ovary. Postoperative recovery was uneventful, the patient was discharged and managed conservatively postoperatively.
勃勒纳瘤是一种罕见的卵巢肿瘤,通常体积较小且为单侧性。大多数病例为良性;所有勃勒纳瘤中不到5%为交界性或增殖性。勃勒纳瘤起源于滤泡上皮,由被纤维组织包围的卵巢移行细胞组成。在此,我们报告一例来自坦桑尼亚北部的49岁绝经前女性病例。该患者因急性腹痛前来我院就诊。她还报告称在就诊前12个月首次发现腹部膨隆。磁共振成像(MRI)显示右侧卵巢有一个21×17×5cm的复杂囊肿,囊壁增厚。影像学检查结果提示为卵巢囊腺瘤;同时还发现了多个肌壁间和浆膜下子宫平滑肌瘤。遂行全腹子宫切除术(TAH)和双侧输卵管卵巢切除术(BSO)。组织病理学检查结果显示右侧卵巢为非典型增殖性交界性勃勒纳瘤。术后恢复顺利,患者出院并接受术后保守治疗。