Tohya Toshimitsu, Tominaga Mariko, Honda Tomoko
Department of Obstetrics and Gynecology, Kumamoto Rosai Hospital, Kumamoto 866-8533, Japan.
Case Rep Obstet Gynecol. 2021 Mar 29;2021:5512951. doi: 10.1155/2021/5512951. eCollection 2021.
Lipomatous tumors are rare among uterine mesenchymal tumors. Due to their rarity, information on the clinical development and histological origin are lacking. We report a pure uterine lipoma and present a review of the relevant literature. We encountered a 72-year-old postmenopausal woman who was referred to our hospital. Computed tomography (CT) and magnetic resonance imaging (MRI) examinations revealed degenerative uterine tumors and a left ovarian cystic tumor with a solid portion. Total hysterectomy and bilateral salpingo-oophorectomy were performed, and postoperative histological examination revealed a uterine lipoma and adenomyosis. The cystic portion was a mucinous cystadenoma, and the solid portion was classified as a Brenner tumor. The postoperative course was uneventful, and the patient was discharged and remained well until follow-up. Our observations suggest that imaging examinations are sufficient for the diagnosis of uterine lipomatous tumors. To the best of our knowledge, the coexistence of a pure uterine lipoma and a mucinous Brenner ovarian tumor has not been documented in the existing literature. The histogenesis of uterine lipomas remains unclear. However, our results, and those from the existing literature, indicate that the mesenchymal stem cells surrounding the perivascular tissue may be implicated, because lipomas of the skin are reported to originate from these cells.
脂肪性肿瘤在子宫间叶性肿瘤中较为罕见。由于其罕见性，缺乏关于临床发展和组织学起源的信息。我们报告一例纯子宫脂肪瘤，并对相关文献进行综述。我们接诊了一位72岁的绝经后女性，她被转诊至我院。计算机断层扫描（CT）和磁共振成像（MRI）检查显示子宫退行性肿瘤和左侧卵巢囊实性肿瘤。行全子宫切除术和双侧输卵管卵巢切除术，术后组织学检查显示为子宫脂肪瘤和子宫腺肌病。囊性部分为黏液性囊腺瘤，实性部分分类为勃勒纳瘤。术后病程平稳，患者出院，随访期间情况良好。我们的观察结果表明，影像学检查足以诊断子宫脂肪性肿瘤。据我们所知，现有文献中尚未记载纯子宫脂肪瘤与黏液性勃勒纳卵巢肿瘤并存的情况。子宫脂肪瘤的组织发生仍不清楚。然而，我们的结果以及现有文献的结果表明，血管周围组织周围的间充质干细胞可能与之有关，因为据报道皮肤脂肪瘤起源于这些细胞。
