Yu Shengyou, Liang Junbo, Ren Qi
Department of Pediatrics, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, China.
Department of Pediatrics, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
Transl Pediatr. 2024 Nov 30;13(11):2077-2087. doi: 10.21037/tp-24-354. Epub 2024 Nov 26.
Gout is the most common inflammatory arthritis in adults, and although gout has been trending younger in recent years, children with gout before the age of 10 years are still rare cases, especially asymptomatic children with gout, making gout in children easy to misdiagnose. This study aimed to describe the clinical characteristics, laboratory tests, imaging findings, and treatment outcomes of a 6-year-old girl with gout.
This case presents a detailed report of a 6-year-old girl diagnosed with primary gout, a condition that is exceedingly rare in pediatric patients, especially those asymptomatic. The patient exhibited a swelling on her right foot that was initially misdiagnosed multiple times before being correctly identified as gout. This patient experienced a marked improvement in their condition following the administration of the prescribed treatment. Furthermore, subsequent follow-up assessments have confirmed the absence of any recurrence. The case highlights the diagnostic challenges faced due to atypical presentations and lack of pediatric-specific diagnostic criteria for hyperuricemia and gout. In this study, we provided a comprehensive discussion on the genetic and metabolic factors contributing to gout, as well as the importance of early and accurate diagnosis to prevent long-term complications.
This case report provides valuable insights into the rare occurrence of gout in children, emphasizing the importance of early and accurate diagnosis and treatment for primary gout in children, emphasizing the need for heightened awareness and accurate diagnostic criteria among pediatric clinicians.
痛风是成人中最常见的炎性关节炎，尽管近年来痛风发病有年轻化趋势，但10岁前儿童痛风仍属罕见病例，尤其是无症状儿童痛风，这使得儿童痛风易被误诊。本研究旨在描述一名6岁痛风女童的临床特征、实验室检查、影像学表现及治疗结果。
本病例详细报告了一名诊断为原发性痛风的6岁女童，这种疾病在儿科患者中极为罕见，尤其是无症状患者。该患者右脚肿胀，最初多次误诊，后被正确诊断为痛风。给予规定治疗后，患者病情显著改善。此外，后续随访评估证实无复发。该病例凸显了因表现不典型以及缺乏针对儿童高尿酸血症和痛风的特异性诊断标准而面临的诊断挑战。在本研究中，我们全面讨论了导致痛风的遗传和代谢因素，以及早期准确诊断对预防长期并发症的重要性。
本病例报告为儿童痛风的罕见情况提供了有价值的见解，强调了儿童原发性痛风早期准确诊断和治疗的重要性，强调儿科临床医生需要提高认识并制定准确的诊断标准。
