Rosa Padilla Natalia L, Enders Brittany, Nelson Nathan C, Negrão Watanabe Tatiane T, Womble Mandy, Traverson Marine
Department of Clinical Sciences (Padilla, Enders, Traverson) and Department of Molecular Biomedical Sciences (Nelson) and Department of Population Health and Pathobiology (Watanabe, Womble), College of Veterinary Medicine, North Carolina State University, 1060 William Moore Drive, Raleigh, North Carolina 27606, USA.
Can Vet J. 2024 Dec;65(12):1228-1233.
This report describes the presentation and management of an incidental primary splenic hemangiosarcoma with hemorrhagic muscle metastasis following an incisional biopsy of a temporalis mass in a dog. In the absence of clinical signs related to the primary splenic lesion, skeletal muscle metastasis of hemangiosarcoma could be misdiagnosed as isolated primary tumor, resulting in failure to provide an accurate prognosis and effective treatment of the primary tumor itself. A thorough diagnostic imaging workup in patients presenting with blood-filled subcutaneous or muscular masses is fundamental to rule out a primary visceral hemangiosarcoma. In addition, the report describes the use of tranexamic acid as an effective local treatment for acute hemorrhage control from a musculoskeletal metastatic lesion that warrants further investigation. Key clinical message: The diagnosis and management of a multi-metastatic splenic hemangiosarcoma in a dog that was presented with hemorrhagic temporal muscle metastasis is reported. An alternative method to control acute hemorrhage using local tranexamic acid is described.
本报告描述了一只犬颞肌肿物切开活检后出现的偶然原发性脾血管肉瘤伴出血性肌肉转移的表现及处理。在没有与原发性脾脏病变相关的临床症状时，血管肉瘤的骨骼肌转移可能会被误诊为孤立的原发性肿瘤，从而导致无法对原发性肿瘤本身做出准确的预后判断和提供有效的治疗。对于出现充满血液的皮下或肌肉肿物的患者，进行全面的诊断性影像学检查对于排除原发性内脏血管肉瘤至关重要。此外，该报告还描述了使用氨甲环酸作为一种有效的局部治疗方法来控制肌肉骨骼转移瘤的急性出血，这值得进一步研究。关键临床信息：报告了一只出现出血性颞肌转移的犬的多转移性脾血管肉瘤的诊断和处理情况。描述了一种使用局部氨甲环酸控制急性出血的替代方法。
