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多发伤患者脊柱损伤手术治疗效果的影响因素分析

Analysis of factors influencing the surgical treatment outcomes of spinal injuries in polytrauma patients.

作者信息

Sun Xiangyao, Huang Jiang, Wang Weiliang, Gan Limeng, Cao Li, Liu Yuqi, Sun Siyuan, Wang Juyong, Lu Shibao

机构信息

Department of Orthopedics, Xuanwu Hospital Capital Medical University, Beijing, People's Republic of China.

National Clinical Research Center for Geriatric Diseases, Beijing, People's Republic of China.

出版信息

Ann Med Surg (Lond). 2024 Oct 28;86(12):6960-6967. doi: 10.1097/MS9.0000000000002704. eCollection 2024 Dec.

Abstract

BACKGROUND

This study aims to analyze the diagnosis and treatment conditions of polytrauma patients with spinal injuries, to clarify the site of the first surgical intervention, the timing of the surgery, and factors influencing prognosis.

METHODS

This study collected and analyzed data on polytrauma patients with spinal injuries who were treated from January 2017 to January 2023. Data collected primarily included basic patient information, treatment strategy-related information, clinical scoring systems, imaging parameters, and prognosis. The impacts of relevant variables on postoperative survival outcomes were analyzed.

RESULTS

This study included 60 patients. There was no significant change in the number of patients rated ASIA grade E after 90 days of admission, while there was a significant increase in those rated grade D (<0.001). Among the groups, patients operated on within less than 12 h had the highest number of ASIA grade A, while those operated on after more than 48 h had the highest number of ASIA grade E (=0.003). The survival rate of patients who underwent their first spinal surgery between 12 and 48 h was significantly better than those operated earlier than 12 h or later than 48 h (=0.047). Patients who experienced hemorrhagic shock postsurgery had the lowest survival rate (<0.001). Only age (=0.004) and the number of surgeries outside the spine (=0.033), as covariates, were significantly correlated with patient mortality (R=0.519).

CONCLUSIONS

Performing spinal surgery too early or too late can adversely affect patient outcomes; the appropriate timing of surgery should be chosen based on the specific characteristics of the patient. In polytrauma patients under emergency conditions, the use of combined surgical treatments should be minimized to prevent the occurrence of a 'second hit'. Patients who experience hemorrhagic shock have the worst postsurgical survival; targeted treatment should be administered upon hospital admission.

摘要

背景

本研究旨在分析合并脊髓损伤的多发伤患者的诊断和治疗情况,明确首次手术干预的部位、手术时机以及影响预后的因素。

方法

本研究收集并分析了2017年1月至2023年1月期间接受治疗的合并脊髓损伤的多发伤患者的数据。收集的数据主要包括患者基本信息、治疗策略相关信息、临床评分系统、影像学参数及预后情况。分析相关变量对术后生存结局的影响。

结果

本研究纳入60例患者。入院90天后,ASIA E级评定患者数量无显著变化,而D级评定患者数量显著增加(<0.001)。在各分组中,入院后12小时内接受手术的患者中ASIA A级数量最多,而48小时后接受手术的患者中ASIA E级数量最多(=0.003)。首次脊髓手术在12至48小时之间进行的患者生存率显著高于手术时间早于12小时或晚于48小时的患者(=0.047)。术后发生失血性休克的患者生存率最低(<0.001)。仅年龄(=0.004)和脊柱外手术次数(=0.033)作为协变量与患者死亡率显著相关(R=0.519)。

结论

过早或过晚进行脊柱手术均会对患者预后产生不利影响;应根据患者具体情况选择合适的手术时机。在紧急情况下的多发伤患者中,应尽量减少联合手术治疗的使用,以防止“二次打击”的发生。发生失血性休克的患者术后生存率最差;入院时应给予针对性治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aee4/11623812/06939af9198f/ms9-86-6960-g001.jpg

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