Khatiwada Abhikanta, Bastakoti Aashish, Kc Sharada, Sharma Usha, Rao Shivali
Department of Radiology, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
Department of General Surgery, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
Ann Med Surg (Lond). 2024 Nov 12;86(12):7469-7473. doi: 10.1097/MS9.0000000000002734. eCollection 2024 Dec.
Phyllodes tumors (PTs) of the breast are rare fibroepithelial neoplasms, accounting for less than 1% of all breast tumors. The WHO classifies PTs into benign, borderline, or malignant categories based on histological features. While benign PTs generally have a favorable prognosis, they carry a risk of transformation into malignant variants, particularly in cases of recurrence.
A 33-year-old female presented with a recurrent benign PT, previously treated with lumpectomy on two occasions. Recent imaging suggested possible malignant transformation, and histopathological examination confirmed a malignant PT.
This case highlights the crucial role of imaging in the early detection of malignant transformation in PTs. Surgical management strategies are discussed, with an emphasis on the potential for recurrent benign tumors to progress to malignancy.
Regular imaging and close follow-up are essential for early detection of malignant transformation in recurrent PTs, guiding timely and appropriate surgical intervention.
乳腺叶状肿瘤（PTs）是罕见的纤维上皮性肿瘤，占所有乳腺肿瘤的比例不到1%。世界卫生组织根据组织学特征将PTs分为良性、交界性或恶性类别。虽然良性PTs通常预后良好，但它们有转变为恶性变体的风险，特别是在复发的情况下。
一名33岁女性患有复发性良性PT，此前曾两次接受肿块切除术治疗。近期影像学检查提示可能发生了恶性转变，组织病理学检查证实为恶性PT。
该病例突出了影像学在PTs恶性转变早期检测中的关键作用。讨论了手术管理策略，重点是复发性良性肿瘤进展为恶性的可能性。
定期影像学检查和密切随访对于复发性PTs恶性转变的早期检测至关重要，有助于指导及时、适当的手术干预。
