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布鲁氏菌病的误诊导致人工瓣膜心内膜炎并发脑血管意外。

A Misdiagnosis of Brucellosis Leads to Prosthetic Valve Endocarditis Complicated by Cerebrovascular Accident.

作者信息

Arian Mahnaz, Tajik Ali, Tashnizi Mohammad Abbasi, Alizada Abdul Rahman

机构信息

Department of Infectious Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Case Rep Infect Dis. 2024 Nov 29;2024:7361317. doi: 10.1155/crdi/7361317. eCollection 2024.

Abstract

Cardiovascular complications of Brucellosis are not common and affecting less than 2% of cases. In clinical practice, endocarditis is the most frequent cardiovascular complication and is responsible for most of the brucellosis-related mortality cases and usually diagnosed lately in the course of the disease with mostly aorta valve involvement. In this case report, we present the case of a 27-year-old woman who was admitted to the hospital with fever, sudden onset right side hemiparesis, and horizontal gaze palsy. During the stroke work up, she underwent cardiac evaluation, including echocardiography with susceptibility to septic emboli with cardiac origin, and the result indicates presence of vegetations on prosthetic aortic valve suggestive of infective endocarditis. Hopefully our patient responded well to combination of heart surgery and antibrucellosis regimen and was finally discharged with stable general condition. It is important to raise awareness of this rare but potentially serious complication of brucellosis, especially in the endemic area, and to emphasize the value of early diagnosis and treatment.

摘要

布鲁氏菌病的心血管并发症并不常见,发生率不到2%。在临床实践中,心内膜炎是最常见的心血管并发症,是大多数布鲁氏菌病相关死亡病例的原因,通常在疾病过程中较晚才被诊断出来,主要累及主动脉瓣。在本病例报告中,我们介绍了一名27岁女性,她因发热、突发右侧偏瘫和水平凝视麻痹入院。在中风检查过程中,她接受了心脏评估,包括对心脏源性脓毒性栓子敏感的超声心动图检查,结果显示人工主动脉瓣上有赘生物,提示感染性心内膜炎。幸运的是,我们的患者对心脏手术和抗布鲁氏菌病治疗方案的联合治疗反应良好,最终在全身状况稳定的情况下出院。提高对这种布鲁氏菌病罕见但潜在严重并发症的认识很重要,尤其是在流行地区,并强调早期诊断和治疗的价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2ce/11623984/d594f5b07d70/CRIID2024-7361317.001.jpg

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