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穆勒D元件的直系同源物。

ortholog of the Muller D element .

作者信息

Mo Mia, Sabb Destiny, LoBello Larissa, Chambers Kayla, Kershaw Kacie, Welles Cameron, Kurucz Joshua, Rhyne Caleb, Nichols Angel, Stanga John, Bedard James E J, Arrigo Cindy

机构信息

Washington University in St. Louis, St. Louis, Missouri, United States.

New Jersey City University, Jersey City, New Jersey, United States.

出版信息

MicroPubl Biol. 2024 Nov 22;2024. doi: 10.17912/micropub.biology.001322. eCollection 2024.

Abstract

The feature with Gene ID 108083276 was determined to be an ortholog of absent, small, or homeotic discs 1 ( ). Two isoforms, ash1-PB and ash1-PC, were constructed on the Muller D element using the GEP annotation protocol. The second coding exon of includes an insertion translated into 18 additional amino acids compared to the protein and is supported by RNA-Seq coverage, the lack of splice junction predictions, and multiple gene predictors. The first intron in both isoforms of contains a well conserved non-canonical GC splice site.

摘要

基因ID为108083276的特征被确定为缺失、微小或同源异型盘1( )的直系同源物。使用GEP注释协议在Muller D元件上构建了两种异构体,ash1-PB和ash1-PC。 的第二个编码外显子包含一个插入序列,与 蛋白相比,该插入序列翻译成18个额外的氨基酸,并且得到RNA-Seq覆盖、缺乏剪接连接预测和多个基因预测器的支持。 两种异构体中的第一个内含子都包含一个保守良好的非经典GC剪接位点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffd/11624501/4f942401cd4b/25789430-2024-micropub.biology.001322.jpg

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