Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA.
Medical Genetics Center (MGZ), Munich, Germany.
Nucleic Acids Res. 2021 Jan 8;49(D1):D1046-D1057. doi: 10.1093/nar/gkaa1070.
For more than two decades, the UCSC Genome Browser database (https://genome.ucsc.edu) has provided high-quality genomics data visualization and genome annotations to the research community. As the field of genomics grows and more data become available, new modes of display are required to accommodate new technologies. New features released this past year include a Hi-C heatmap display, a phased family trio display for VCF files, and various track visualization improvements. Striving to keep data up-to-date, new updates to gene annotations include GENCODE Genes, NCBI RefSeq Genes, and Ensembl Genes. New data tracks added for human and mouse genomes include the ENCODE registry of candidate cis-regulatory elements, promoters from the Eukaryotic Promoter Database, and NCBI RefSeq Select and Matched Annotation from NCBI and EMBL-EBI (MANE). Within weeks of learning about the outbreak of coronavirus, UCSC released a genome browser, with detailed annotation tracks, for the SARS-CoV-2 RNA reference assembly.
二十多年来，UCSC 基因组浏览器数据库（https://genome.ucsc.edu）一直向研究界提供高质量的基因组学数据可视化和基因组注释。随着基因组学领域的发展和更多数据的出现，需要新的显示模式来适应新技术。去年发布的新功能包括 Hi-C 热图显示、VCF 文件的分相家族 trio 显示以及各种跟踪可视化改进。为了保持数据的最新，对基因注释的新更新包括 GENCODE Genes、NCBI RefSeq Genes 和 Ensembl Genes。为人类和小鼠基因组添加的新数据轨道包括 ENCODE 候选顺式调控元件注册中心、真核启动子数据库中的启动子以及来自 NCBI 和 EMBL-EBI（MANE）的 NCBI RefSeq Select 和匹配注释。在了解到冠状病毒爆发后的几周内，UCSC 发布了一个带有详细注释轨道的 SARS-CoV-2 RNA 参考组装的基因组浏览器。
