Tao Qingqing, Zhao Zhengyang, Yang Rui, Li Qin, Qiao Jie
Peking University Health Science Center-Weifang Joint Research Center for Maternal and Child Health, Department of Maternal and Child Health, School of Public Health, Peking University, Beijing 100191, China.
Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.
Heliyon. 2024 Nov 19;10(22):e40503. doi: 10.1016/j.heliyon.2024.e40503. eCollection 2024 Nov 30.
Fine particulate matter (PM) pollution has raised significant public concerns, especially for vulnerable populations. Studies have indicated the association between PM and ovarian disorders, although the mechanisms underlying the effects have not yet been fully elucidated. In this review, we elucidated three main conditions pertaining to ovarian function that may result from exposure to PM diminished ovarian reserve, polycystic ovary syndrome, and infertility. Specific effects of ovarian disorders caused by PM are discussed, including reactive oxygen species, apoptosis, DNA damage, and inflammation.
细颗粒物（PM）污染引起了公众的广泛关注，尤其是对弱势群体而言。研究表明了PM与卵巢疾病之间的关联，尽管其影响机制尚未完全阐明。在本综述中，我们阐明了暴露于PM可能导致的与卵巢功能相关的三种主要情况——卵巢储备功能减退、多囊卵巢综合征和不孕症。文中讨论了由PM引起的卵巢疾病的具体影响，包括活性氧、细胞凋亡、DNA损伤和炎症。
