Sivritepe Ridvan, Siyer Ozge Kiran, Tiril Serhat Mert, Basat Sema Ucak
Department of Internal Medicine, Istanbul Medipol University Faculty of Medicine, Istanbul, Turkiye.
Department of Endocrinology, University of Health Sciences, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkiye.
North Clin Istanb. 2024 Nov 22;11(6):593-599. doi: 10.14744/nci.2024.48642. eCollection 2024.
Dynapenia is a condition characterized by decreased muscle strength and function in older adults that is not due to a specific underlying disease or medical condition. Dynapenia is common among older adults and has significant health effects, including functional impairment, disability, increased risk of falls, hospitalization, and death. Oxidative stress, mitochondrial dysfunction and chronic inflammation are involved in the etiopathophysiology of dynapenia. Diagnosis of dynapenia is based on the evaluation of muscle strength and function using methods such as hand grip strength, timed up and go test and short physical performance battery. Management of dynapenia involves a multifaceted approach that includes exercise, nutrition, pharmacological interventions, management of underlying medical conditions, and fall prevention strategies. With appropriate interventions, older adults with dynapenia can improve muscle strength and function, reduce the risk of falls and disability, and maintain their independence and quality of life.
肌肉减少症是一种在老年人中表现为肌肉力量和功能下降的病症,并非由特定的潜在疾病或医疗状况引起。肌肉减少症在老年人中很常见,并且对健康有重大影响,包括功能障碍、残疾、跌倒、住院和死亡风险增加。氧化应激、线粒体功能障碍和慢性炎症参与了肌肉减少症的病理生理过程。肌肉减少症的诊断基于使用诸如握力、计时起立行走测试和简短体能测试等方法对肌肉力量和功能进行评估。肌肉减少症的管理涉及多方面的方法,包括运动、营养、药物干预、基础疾病的管理以及跌倒预防策略。通过适当的干预,患有肌肉减少症的老年人可以提高肌肉力量和功能,降低跌倒和残疾的风险,并维持他们的独立性和生活质量。