Qiao Wenbo, Xiang Xinyue, Deng Qionglin, Li Huijuan, Lin Yan, Chu Junqing
Department of Nursing, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Department of Respiratory Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Respir Med Case Rep. 2024 Nov 21;52:102145. doi: 10.1016/j.rmcr.2024.102145. eCollection 2024.
Penicillium Marneffei (PM) infections often present with nonspecific clinical manifestations, and severe respiratory failure after infection is particularly uncommon. This case report a patient who developed severe respiratory failure due to PM infection post-kidney transplantation. Additionally, it delves into pertinent treatment measures and nursing strategies. The patient was diagnosed with PM infection, respiratory failure, and post-kidney transplant status. The treatment measures included the drug therapy and dynamic adjustment the application of nitric oxide combined with ECMO-prone position ventilation, balancing bleeding and thrombosis risks, early enteral nutrition and adaptive progression to pulmonary rehabilitation exercises. This case is a valuable reference for critical care in similar conditions.
马尔尼菲篮状菌（PM）感染通常表现为非特异性临床表现，感染后出现严重呼吸衰竭尤为罕见。本病例报告了一名肾移植术后因PM感染而发生严重呼吸衰竭的患者。此外，还深入探讨了相关的治疗措施和护理策略。该患者被诊断为PM感染、呼吸衰竭和肾移植术后状态。治疗措施包括药物治疗、动态调整一氧化氮联合体外膜肺氧合（ECMO）俯卧位通气的应用、平衡出血和血栓形成风险、早期肠内营养以及逐步过渡到肺康复锻炼。本病例为类似情况下的重症监护提供了有价值的参考。
