Kurniawati Yuli, Yahya Yulia Farida, Fadhila Aryati, Rahmanda M Rezi, Nursyarifah Nyimas, Alisa Nanda Safira
Department of Dermatology, Venereology, and Aesthetics Mohammad Hoesin Hospital, Palembang, South Sumatra, Indonesia.
Faculty of Medicine Universitas Sriwijaya, Department of Dermatology, Venereology, and Aesthetics, Palembang, South Sumatra, Indonesia.
J Lasers Med Sci. 2024 Nov 24;15:e56. doi: 10.34172/jlms.2024.56. eCollection 2024.
Striae distensae (SD) are a skin disorder characterized by linear atrophic depression of the dermis due to stretching of the skin. There are various SD therapy modalities, namely topical therapy, peeling, microneedling, platelet-rich plasma, and laser. Until now, there has been no standard therapy for SD, but several therapeutic modalities can reduce clinical symptoms, so knowledge about the current management of SD is needed. The research method used an experimental research design with consecutive sampling technique in SD patients at the Dermatology, Venereology and Aesthetics clinic of Mohammad Hoesin Hospital, Palembang, during the research period. This study aimed to determine the effectiveness of combination therapy with fractional CO laser and in SD. This study included 22 SD patients who met the inclusion criteria and received combination therapy with fractional CO laser and . The results of the analysis of differences in the Index of Striae Distensae Assessment (INA) score, Dermatology Life Quality Index (DLQI) score and VAS score revealed that there was a significant difference in the mean decrease in the INA score between the baseline and week 12 (=0.014), as well as in the DLQI score between the baseline and week 12 (=0.000). There was a significant difference in the mean VAS score between the baseline and week 4 (=0.000). These findings indicate that the combination of fractional CO laser and topical effectively reduces the severity of SD, improves patients' quality of life, and decreases associated pain. Further studies could explore long-term effects and optimize treatment protocols for even better outcomes.
膨胀纹（SD）是一种皮肤疾病，其特征是由于皮肤拉伸导致真皮出现线性萎缩凹陷。膨胀纹有多种治疗方式，即局部治疗、皮肤剥脱术、微针治疗、富血小板血浆治疗和激光治疗。到目前为止，膨胀纹尚无标准治疗方法，但几种治疗方式可减轻临床症状，因此需要了解膨胀纹的当前治疗方法。在研究期间，研究方法采用实验性研究设计，并在巨港穆罕默德·霍辛医院皮肤科、性病科和美容科对膨胀纹患者采用连续抽样技术。本研究旨在确定分次二氧化碳激光与[此处原文缺失相关内容]联合治疗膨胀纹的有效性。本研究纳入了22例符合纳入标准并接受分次二氧化碳激光与[此处原文缺失相关内容]联合治疗的膨胀纹患者。膨胀纹评估指数（INA）评分、皮肤病生活质量指数（DLQI）评分和视觉模拟评分（VAS）的差异分析结果显示，基线与第12周之间INA评分的平均下降存在显著差异（P = 0.014），基线与第12周之间DLQI评分也存在显著差异（P = 0.000）。基线与第4周之间VAS评分的平均差异有统计学意义（P = 0.000）。这些结果表明，分次二氧化碳激光与局部[此处原文缺失相关内容]联合治疗可有效减轻膨胀纹的严重程度,改善患者生活质量，并减轻相关疼痛。进一步的研究可以探索长期效果并优化治疗方案以获得更好的结果。
