Ochiai Shunsuke, Yamada Manabu, Suga Kenichiro, Nishikawa Masafumi, Asoda Seiji
Division of Dentistry and Oral Surgery, Shizuoka Cancer Center, Shizuoka, JPN.
Department of Dentistry and Oral Surgery, National Hospital Organization, Tochigi Medical Center, Tochigi, JPN.
Cureus. 2024 Nov 8;16(11):e73263. doi: 10.7759/cureus.73263. eCollection 2024 Nov.
Although myoepithelioma is defined as a benign tumour made up primarily of neoplastic myoepithelial cells, its actual histopathological characteristics are highly diverse. It can be considered a rare disease. The most common site of occurrence is the parotid gland, followed by the minor salivary glands of the palate. Very little has been reported about its occurrence in the buccal mucosa. We present a case of a 55-year-old woman with myoepithelioma arising in the buccal mucosa who was referred to our hospital for swelling of the buccal mucosa. Contrast-enhanced computed tomography revealed a mass measuring approximately 18 mm in diameter in the left lateral buccal mucosa, and the interior of the mass showed slight heterogeneous enhancement. Magnetic resonance imaging revealed an almost low signal intensity comparable to that of the muscle on T1-weighted imaging and an irregular mixture of low and high signal intensities on T2-weighted imaging. The tumour was diagnosed as a pleomorphic adenoma based on biopsy results and resected under general anaesthesia. The final diagnosis was myoepithelioma, which requires careful differentiation from pleomorphic adenoma. At 32 months after surgery, no evidence of recurrence was detected.
尽管肌上皮瘤被定义为主要由肿瘤性肌上皮细胞组成的良性肿瘤,但其实际组织病理学特征却高度多样。它可被视为一种罕见疾病。最常见的发病部位是腮腺,其次是腭部的小唾液腺。关于其在颊黏膜中的发生情况报道极少。我们报告一例55岁女性,其颊黏膜发生肌上皮瘤,因颊黏膜肿胀转诊至我院。增强计算机断层扫描显示左侧颊黏膜有一个直径约18mm的肿块,肿块内部呈轻度不均匀强化。磁共振成像显示在T1加权成像上几乎呈与肌肉相当的低信号强度,在T2加权成像上呈低信号和高信号强度的不规则混合。根据活检结果,该肿瘤被诊断为多形性腺瘤,并在全身麻醉下切除。最终诊断为肌上皮瘤,这需要与多形性腺瘤仔细鉴别。术后32个月,未发现复发迹象。