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中度和重度支气管哮喘患者运动能力评估:初步前瞻性观察研究

Assessment of Exercise Capacity in Patients Diagnosed with Moderate and Severe Bronchial Asthma: Preliminary Prospective Observational Study.

作者信息

Bajer Weronika Alicja, Majewska-Pulsakowska Marta, Paprocka-Borowicz Małgorzata, Wytrychowski Krzysztof, Taradaj Jakub, Ptaszkowski Kuba

机构信息

Faculty of Health Sciences, Department of Physiotherapy, Wroclaw Medical University, Wroclaw, Lower Silesian Voivodeship, Poland.

Faculty of Medicine, Clinical Department of Internal Medicine, Pneumology and Allergology, Wroclaw Medical University, Wroclaw, Lower Silesian Voivodeship, Poland.

出版信息

J Asthma Allergy. 2024 Dec 3;17:1247-1258. doi: 10.2147/JAA.S458717. eCollection 2024.

DOI:10.2147/JAA.S458717
PMID:39651369
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11624687/
Abstract

PURPOSE

The main objective of the study was to assess exercise capacity and physical activity levels in patients with bronchial asthma compared to a control group without asthma, as well as to investigate how asthma severity affects the results of the 6MWT and physical activity as measured by the IPAQ questionnaire.

PATIENTS AND METHODS

A total of 63 individuals were studied, divided into two groups: Group A, consisting of 33 individuals with bronchial asthma, and Group B, consisting of 30 individuals from the general population without bronchial asthma. In both groups, the following assessments were performed: The Six-Minute Walk Test (6MWT), The International Physical Activity Questionnaire (IPAQ) and the Borg rating of perceived exertion scale (the Borg RPE scale) ABB.

RESULTS

It was demonstrated that patients with moderate asthma covered more distance during the 6MWT than patients diagnosed with severe asthma. The difference in metres covered between the two groups was statistically significant (p < 0.001), which could be observed during the walk test. The results indicate that a larger proportion of patients with asthma (76%) fall into the insufficient physical activity category compared to those without asthma (24%). Conversely, a higher percentage of non-asthmatic individuals (66.67%) report sufficient physical activity compared to asthmatic patients (33.33%)(P=0.005).

CONCLUSION

This study demonstrated that asthma severity significantly impacts exercise capacity, as shown by shorter distances covered in the 6-minute walk test (6MWT) among patients with severe asthma. While overall physical activity levels (measured by the IPAQ) were not significantly different between asthma and non-asthma groups, asthma patients exhibited significantly more sitting time, suggesting a more sedentary lifestyle.

摘要

目的

本研究的主要目的是评估支气管哮喘患者与无哮喘对照组的运动能力和身体活动水平,并调查哮喘严重程度如何影响6分钟步行试验(6MWT)结果以及通过国际体力活动问卷(IPAQ)测量的身体活动情况。

患者与方法

共研究了63名个体,分为两组:A组由33名支气管哮喘患者组成,B组由30名无支气管哮喘的普通人群组成。两组均进行了以下评估:六分钟步行试验(6MWT)、国际体力活动问卷(IPAQ)和伯格主观用力程度量表(伯格RPE量表)ABB。

结果

结果表明,中度哮喘患者在6MWT中行走的距离比重度哮喘患者更远。两组之间行走距离的差异具有统计学意义(p < 0.001),这在步行试验中可以观察到。结果表明,与无哮喘患者(24%)相比,哮喘患者中更大比例(76%)属于身体活动不足类别。相反,与哮喘患者(33.33%)相比,非哮喘个体中报告有足够身体活动的比例更高(66.67%)(P = 0.005)。

结论

本研究表明,哮喘严重程度显著影响运动能力,重度哮喘患者在6分钟步行试验(6MWT)中行走的距离较短即表明了这一点。虽然哮喘组和非哮喘组之间总体身体活动水平(通过IPAQ测量)没有显著差异,但哮喘患者的久坐时间明显更长,这表明其生活方式更久坐。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b1/11624687/54fb8055792c/JAA-17-1247-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b1/11624687/6e24b74d870a/JAA-17-1247-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b1/11624687/e4166b3e87ce/JAA-17-1247-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b1/11624687/54fb8055792c/JAA-17-1247-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b1/11624687/6e24b74d870a/JAA-17-1247-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b1/11624687/e4166b3e87ce/JAA-17-1247-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b1/11624687/54fb8055792c/JAA-17-1247-g0003.jpg

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本文引用的文献

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Increasing physical activity in severe asthma: a systematic review and meta-analysis.增加严重哮喘患者的身体活动:系统评价和荟萃分析。
Eur Respir J. 2022 Dec 15;60(6). doi: 10.1183/13993003.00546-2022. Print 2022 Dec.
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Can long-term regular physical activity improve health outcomes among adults with asthma-evidence from a systematic review and Bayesian meta-analysis.长期规律的体育活动能否改善哮喘成年人的健康状况——一项系统评价和贝叶斯荟萃分析的证据
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哮喘领域的进展:对哮喘自然史、危险因素、潜在机制及临床管理的新认识。
J Allergy Clin Immunol. 2021 Dec;148(6):1430-1441. doi: 10.1016/j.jaci.2021.10.001. Epub 2021 Oct 14.
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Chest. 2020 Mar;157(3):603-611. doi: 10.1016/j.chest.2019.10.014. Epub 2019 Nov 2.
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Usefulness of mannitol challenge testing for diagnosing asthma in everyday clinical practice.甘露醇激发试验在日常临床实践中诊断哮喘的作用。
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Epidemiology and risk factors for asthma.哮喘的流行病学及危险因素
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Exercise Improves Physical Activity and Comorbidities in Obese Adults with Asthma.运动改善肥胖哮喘患者的身体活动和合并症。
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