Toppenberg Alexandra G L, Lodder Wouter L, Plaat Robert E, Schwandt Leonora Q
Department of Otorhinolaryngology - Head and Neck Surgery, Medical Center Leeuwarden, Henri Dunantweg 2, 8934AD, Leeuwarden, The Netherlands.
Department of Otorhinolaryngology - Head and Neck Surgery, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
Eur Arch Otorhinolaryngol. 2025 Mar;282(3):1459-1468. doi: 10.1007/s00405-024-09102-0. Epub 2024 Dec 9.
Obstructive Sleep Apnea (OSA) is usually caused by collapse of the base of tongue (BOT) and impacts patients' overall health. Despite current conventional therapies, some patients do not achieve satisfactory results. Reduction of BOT using Trans Oral Robotic Surgery (TORS) emerges as a promising treatment. We evaluated the patient reported and clinical outcomes of TORS for OSA.
We performed a retrospective cohort study of patients treated from 2018 to 2021 in a non-academic general hospital. Patients were eligible for TORS when apnea hypopnea index (AHI) was >5 in combination with obstruction at BOT level. Patients were included when 1-year follow up respiratory polygraphy was available. Changes in Epworth Sleepiness Scale (ESS), Functional Outcomes of Sleep Questionnaire (FOSQ-35), MD Anderson Dysphagia Inventory (MDADI) scores and postoperative complications were evaluated. Surgical success rates were obtained.
Out of 56 patients, 28 patients of which 22 (78.6%) males and 6 (21.4%) females, with OSA severity ranging from mild to severe and mean age of 49 (SD 11.8) with a median BMI of 28.1 (IQR 26.9-32.1) were included. ESS score declined from mean 5.9 (SD 3.8) to 2.2 (SD 2.0) (p<0.00). FOSQ-35 scores were all declined (p<0.05). MDADI scores were in normal range (80-100) and remained stable (p = 0.44). In 23 (82.1%) patients no postoperative complications were observed. Surgical success rates were 86%.
TORS demonstrate to be effective and safe in OSA patients, and it can be used in both patients who are unresponsive to conventional therapies or as a primary therapy.
阻塞性睡眠呼吸暂停(OSA)通常由舌根(BOT)塌陷引起,影响患者的整体健康。尽管有目前的传统疗法,但一些患者并未取得满意的效果。经口机器人手术(TORS)减少舌根塌陷成为一种有前景的治疗方法。我们评估了TORS治疗OSA的患者报告结局和临床结局。
我们对2018年至2021年在一家非学术性综合医院接受治疗的患者进行了一项回顾性队列研究。当呼吸暂停低通气指数(AHI)>5且伴有BOT水平阻塞时,患者符合TORS治疗条件。当有1年随访的呼吸多导睡眠图时,患者被纳入研究。评估爱泼华嗜睡量表(ESS)、睡眠问卷功能结局(FOSQ-35)、MD安德森吞咽障碍量表(MDADI)评分的变化以及术后并发症。获得手术成功率。
56例患者中,纳入了28例患者,其中男性22例(78.6%),女性6例(21.4%),OSA严重程度从轻度到重度不等,平均年龄49岁(标准差11.8),BMI中位数为28.1(四分位间距26.9 - 32.1)。ESS评分从平均5.9(标准差3.8)降至2.2(标准差2.0)(p<0.00)。FOSQ-35评分均下降(p<0.05)。MDADI评分在正常范围(80 - 100)且保持稳定(p = 0.44)。23例(82.1%)患者未观察到术后并发症。手术成功率为86%。
TORS在OSA患者中显示出有效且安全,可用于对传统疗法无反应的患者或作为一线治疗。