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成人舌基手术治疗睡眠呼吸暂停的安全性:YO-IFOS 研究组的系统评价和荟萃分析。

Safety of tongue base procedures for sleep apnoea in adults: A systematic review and metanalysis from the YO-IFOS study group.

机构信息

Service of Otolaryngology, Rhinology Department, Hospital Complex of Santiago de Compostela,Spain.

Sleep Apnea Study Group of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), Paris,France; Service of Otolaryngology, Rhinology Department, Hospital Complex of Santiago de Compostela,Spain.

出版信息

Acta Otorrinolaringol Esp (Engl Ed). 2022 Nov-Dec;73(6):384-393. doi: 10.1016/j.otoeng.2021.10.004.

Abstract

OBJECTIVE

Tongue base and hypopharynx are the major sites of obstruction in OSA patients with failed palatal surgery. In recent years, several minimally invasive procedures have been developed to address tongue base obstruction. However, the research focus has consistently been on the effectiveness of surgery in reducing obstructive sleep apnoea rather than on postoperative complications. In this systematic review and metanalysis we aim to review the complication rate of minimally invasive base of tongue procedures for OSAS in adults.

DATA SOURCES

PubMed (Medline), the Cochrane Library, EMBASE, Scopus, SciELO and Trip Database.

REVIEW METHODS

Data sources were checked by three authors of the YO-IFOS sleep apnoea study group. Three authors extracted the data. Main outcome was expressed as the complication rate and 95% confidence interval for each surgical technique.

RESULTS

20 studies (542 patients) met the inclusion criteria. The mean complication rate is 12.79%; 4.65% for minor complications, 6.42% if they are moderate, and 1.77% if severe. The most reported complication overall is infection, in 1.95% of cases, followed by transient swallowing disorder, occurring in 1.30% of the total sample.

CONCLUSION

The heterogeneity amongst the included studies prevents us from obtaining solid conclusions. The available evidence suggests that minimally invasive base of tongue procedures may present a wide spectrum of complication rates, ranging from 4.4% in tongue base radiofrequency to up to 42.42% in tongue base ablation.

摘要

目的

舌根部和下咽是腭后手术失败的 OSA 患者的主要阻塞部位。近年来,已经开发了几种微创程序来解决舌基阻塞问题。然而,研究的重点一直是手术在减少阻塞性睡眠呼吸暂停方面的有效性,而不是术后并发症。在这项系统回顾和荟萃分析中,我们旨在回顾成人 OSA 患者微创舌根手术的并发症发生率。

数据来源

PubMed(Medline)、Cochrane 图书馆、EMBASE、Scopus、SciELO 和 Trip 数据库。

审查方法

YO-IFOS 睡眠呼吸暂停研究小组的三位作者检查了数据源。三位作者提取了数据。主要结果表示为每种手术技术的并发症发生率和 95%置信区间。

结果

20 项研究(542 名患者)符合纳入标准。平均并发症发生率为 12.79%;轻度并发症为 4.65%,中度并发症为 6.42%,重度并发症为 1.77%。总体上报告最多的并发症是感染,占 1.95%,其次是暂时性吞咽障碍,总样本中占 1.30%。

结论

纳入研究之间的异质性使我们无法得出确凿的结论。现有证据表明,微创舌根手术可能会出现各种并发症发生率,从舌基射频的 4.4%到舌基消融的 42.42%不等。

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