DeCherney A H, Silidker J S, Mezer H C, Tarlatzis B C
Fertil Steril. 1985 Jan;43(1):82-5. doi: 10.1016/s0015-0282(16)48322-6.
Consideration of reproductive potential following multiple ectopic pregnancies is important in counseling patients and when choosing a conservative surgical approach (salpingotomy, salpingostomy), partial salpingectomy, or in vitro fertilization. The cases of 336 patients at Yale-New Haven Hospital who had ectopic pregnancies between 1976 and 1981 were evaluated. Thirty-two patients (9.5%) had two ectopic pregnancies. Twenty-three patients (71.8%) were followed. Six of these (26.1%) were not able to conceive because of surgical sterilization, and four (17.4%) were not trying to conceive. Of those 13 patients (56.5%) actively trying to conceive and having at least one tube remaining, 4 (30.8%) had term intrauterine gestations. One had a third ectopic gestation, which represented 20% of all conceptions, or 7.7% of those individuals trying to conceive. Our results indicate that although the reproductive potential after two ectopic pregnancies is poor, viable pregnancies do occur, and the repeat ectopic pregnancy rate is not high enough to preclude a repeat conservative surgical approach.
在为患者提供咨询以及选择保守手术方法(输卵管切开术、输卵管造口术)、部分输卵管切除术或体外受精时,考虑多次异位妊娠后的生殖潜能非常重要。对耶鲁 - 纽黑文医院1976年至1981年间发生异位妊娠的336例患者的病例进行了评估。32例患者(9.5%)有两次异位妊娠。23例患者(71.8%)接受了随访。其中6例(26.1%)因手术绝育无法受孕,4例(17.4%)未尝试受孕。在那些积极尝试受孕且至少保留一条输卵管的13例患者(56.5%)中,4例(30.8%)有足月宫内妊娠。1例发生了第三次异位妊娠,占所有妊娠的20%,或占那些尝试受孕者的7.7%。我们的结果表明,尽管两次异位妊娠后的生殖潜能较差,但确实会发生存活妊娠,且重复异位妊娠率不足以排除再次采用保守手术方法。