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先天性梅毒的骨骼异常:一例报告。

Bone abnormalities in congenital syphilis: A case report.

作者信息

Tascón-Barona Andrés Hernando, Coral-Rivera Nathalia Sofia

机构信息

Departamento de Radiología e Imágenes Diagnósticas, Fundación Valle del Lili, Cali, Colombia.

Centro de Investigaciones Clínicas, Fundación Valle del Lili, Cali, Colombia.

出版信息

Radiol Case Rep. 2024 Nov 22;20(2):871-873. doi: 10.1016/j.radcr.2024.10.137. eCollection 2025 Feb.

DOI:10.1016/j.radcr.2024.10.137
PMID:39654573
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11625107/
Abstract

Congenital syphilis, caused by , can be transmitted from mother to fetus at any stage of pregnancy, leading to significant neonatal complications. This case report describes a 33-week preterm newborn with a history of untreated gestational syphilis in the mother. At birth, the newborn's serological tests were positive for syphilis, and radiographs of the long bones revealed metaphyseal abnormalities consistent with metaphysitis. These findings highlight the importance of early radiological evaluation in newborns with suspected congenital syphilis. Despite the absence of clinical symptoms, X-rays can detect bone changes indicative of early complications, enabling timely diagnosis and intervention to improve outcomes. This case emphasizes the crucial role of radiographic imaging in the management of congenital syphilis.

摘要

先天性梅毒由[病因未提及]引起,可在孕期任何阶段从母亲传播给胎儿,导致严重的新生儿并发症。本病例报告描述了一名33周早产新生儿,其母亲有未经治疗的妊娠梅毒病史。出生时,新生儿梅毒血清学检测呈阳性,长骨X线片显示干骺端异常,符合干骺炎表现。这些发现凸显了对疑似先天性梅毒新生儿进行早期影像学评估的重要性。尽管没有临床症状,但X线可检测到提示早期并发症的骨骼变化,从而实现及时诊断和干预以改善预后。本病例强调了影像学检查在先天性梅毒管理中的关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54da/11625107/6e035232b173/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54da/11625107/6e035232b173/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54da/11625107/6e035232b173/gr1.jpg

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本文引用的文献

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Congenital Syphilis and the Orthopaedic Perspective: A Case Report.先天性梅毒与矫形科视角:病例报告。
JBJS Case Connect. 2024 May 3;14(2). doi: e24.00017. eCollection 2024 Apr 1.
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[Congenital bone syphilis from a historical perspective].
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Congenital Syphilis-An Illustrative Review.先天性梅毒——一篇例证性综述。
Children (Basel). 2023 Jul 29;10(8):1310. doi: 10.3390/children10081310.
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Maternal and perinatal risk factors associated with congenital syphilis.与先天性梅毒相关的母婴和围产期危险因素。
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Rev Bras Enferm. 2021 Jul 14;74(4):e20190318. doi: 10.1590/0034-7167-2019-0318. eCollection 2021.
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