Shao Xinxin, Xi Yawei, Pan Lijie, Li Xinru, Lin Qianxin, Tian Keming, Wang Rui, Gao Yutong, Gao Hainan, Tan Zili, Zhu Xiangyu
School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, China.
Acupuncture and Rehabilitation Department, Liangxiang Hospital of Beijing Fangshan District, Beijing, China.
Front Neurosci. 2024 Nov 25;18:1467595. doi: 10.3389/fnins.2024.1467595. eCollection 2024.
To explore the effectiveness of Tai Chi on cognitive function in patients with mild cognitive impairment (MCI).
According to the PRISMA guidelines, randomized controlled trial (RCT) literature on the efficacy of Tai Chi on MCI patients was searched in China National Knowledge Network (CNKI), China Biomedical Literature Database (CBM), Wanfang Data, China Scientific Journal Database (VIP), PubMed, Embase, Duxiu Database, Web of Science and Cochrane Library from their inception to April 2024. The risk of bias in each study was appraised using the Cochrane risk-of-bias tool using Revman 5.4. Random effect model or fixed effect model was used to compare the effects of Tai Chi and control conditions on baseline and post-intervention assessment of cognitive function. Meta-analysis was performed using Stata15.0 software.
Nine studies fulfilled the inclusion criteria. Tai Chi significantly improved Montreal Cognitive Assessment (MoCA, SMD, 1.43, < 0.00001), Delayed Recall Test (DRT, SMD, 0.90, < 0.00001), verbal fluency test (VFT, SMD, 0.40, < 0.00001), and Trail Making Test (TMT, SDM, -0.69, < 0.00001) in MCI patients. Subgroup analyses showed that 24-forms Tai Chi was more effective than 8-forms Tai Chi in improving MoCA (SMD, 1.89, < 0.00001) and 10-forms Tai Chi was more effective than 24-forms Tai Chi in improving DRT (SMD, 1.53, < 0.00001).
Tai Chi improved cognitive function in MCI patients, and Tai Chi types might be the influence factor on Tai Chi improving the global cognitive function and memory function in MCI patients.
探讨太极拳对轻度认知障碍（MCI）患者认知功能的有效性。
根据PRISMA指南，在中国知网（CNKI）、中国生物医学文献数据库（CBM）、万方数据、维普中文科技期刊数据库（VIP）、PubMed、Embase、读秀数据库、Web of Science和Cochrane图书馆中检索从建库至2024年4月关于太极拳对MCI患者疗效的随机对照试验（RCT）文献。使用Revman 5.4软件中的Cochrane偏倚风险工具评估每项研究的偏倚风险。采用随机效应模型或固定效应模型比较太极拳与对照条件对认知功能基线及干预后评估的影响。使用Stata15.0软件进行Meta分析。
9项研究符合纳入标准。太极拳显著改善了MCI患者的蒙特利尔认知评估（MoCA，标准化均数差[SMD]，1.43，<0.00001）、延迟回忆测验（DRT，SMD，0.90，<0.00001）、语言流畅性测验（VFT，SMD，0.40，<0.00001）和连线测验（TMT，SMD，-0.69，<0.00001）。亚组分析显示，24式太极拳在改善MoCA方面比8式太极拳更有效（SMD，1.89，<0.00001），10式太极拳在改善DRT方面比24式太极拳更有效（SMD，1.53，<0.00001）。
太极拳改善了MCI患者的认知功能，太极拳类型可能是影响太极拳改善MCI患者整体认知功能和记忆功能的因素。
