Građanin Amina, Jelešković Azra, Džemidžić Vildana, Tiro Alisa, Redžepagić-Vražalica Lejla
Department of Orthodontics, University of Sarajevo - Faculty of Dentistry with Dental Clinical Center, Sarajevo, Bosnia and Herzegovina.
Acta Med Acad. 2024 Dec;53(3):286-292. doi: 10.5644/ama2006-124.448.
The goal of this review was to determine the effectiveness of different types of monobloc and bibloc mandibular advancement device (MAD) devices in the treatment of all forms of obstructive sleep apnea (OSA), by reviewing the available literature.
A systematic literature search was performed in PubMed, ResearchGate, NCBI and Google Scholar databases. The search included articles in English, published in the inclusive time period from 2000 to 2024.
A total of 13 studies were analyzed that directly compared the effectiveness of monobloc and bibloc devices. The studies were published in the period from 2000 to 2024, and included crossover and parallel randomized controlled trials, as well as cross and parallel cohort studies. Out of the 13 studies, four were classified as RCT parallel studies, six were RCT crossover studies, two cohort parallel studies, and one cohort crossover study. The duration of the studies was variable, ranging from four weeks to one year, with six studies having a so-called "washout period" between the use of monobloc and bibloc MAD devices.
Both monobloc and bibloc devices show significant success rates in the treatment of mild to moderate OSA.
本综述的目的是通过回顾现有文献，确定不同类型的一体式和双体式下颌前移装置（MAD）在治疗各种形式的阻塞性睡眠呼吸暂停（OSA）中的有效性。
在PubMed、ResearchGate、NCBI和谷歌学术数据库中进行了系统的文献检索。检索范围包括2000年至2024年期间发表的英文文章。
共分析了13项直接比较一体式和双体式装置有效性的研究。这些研究发表于2000年至2024年期间，包括交叉和平行随机对照试验，以及交叉和平行队列研究。在这13项研究中，4项为随机对照试验平行研究，6项为随机对照试验交叉研究，2项为队列平行研究，1项为队列交叉研究。研究持续时间各不相同，从四周到一年不等，其中六项研究在使用一体式和双体式MAD装置之间有一个所谓的“洗脱期”。
一体式和双体式装置在治疗轻度至中度OSA方面均显示出显著的成功率。
