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The potential of nanoparticle-based siRNA delivery in breast cancer treatment.

作者信息

Bakhtiar Athirah, Kuan Xi-Yuen, Chowdhury Ezharul Hoque

机构信息

School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia.

Jeffrey Cheah School of Medicine & Health Sciences, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia.

出版信息

Nanomedicine (Lond). 2025 Mar;20(6):531-533. doi: 10.1080/17435889.2024.2440302. Epub 2024 Dec 10.

DOI:10.1080/17435889.2024.2440302
PMID:39655626
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11881832/
Abstract
摘要

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本文引用的文献

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Drug Deliv. 2024 Dec;31(1):2425156. doi: 10.1080/10717544.2024.2425156. Epub 2024 Nov 8.
2
Biomimetic Modification of siRNA/Chemo Drug Nanoassemblies for Targeted Combination Therapy in Breast Cancer.仿生修饰的 siRNA/化疗药物纳米组装体用于乳腺癌的靶向联合治疗。
ACS Appl Mater Interfaces. 2024 Nov 6;16(44):59765-59776. doi: 10.1021/acsami.4c11064. Epub 2024 Oct 24.
3
Enhancing siRNA cancer therapy: Multifaceted strategies with lipid and polymer-based carrier systems.增强 siRNA 癌症治疗：基于脂质和聚合物载体系统的多方面策略。
Int J Pharm. 2024 Sep 30;663:124545. doi: 10.1016/j.ijpharm.2024.124545. Epub 2024 Aug 2.
4
NMR-based analysis of impact of siRNA mixing conditions on internal structure of siRNA-loaded LNP.基于 NMR 的分析表明，siRNA 混合条件对负载 siRNA 的 LNPs 内部结构的影响。
J Control Release. 2024 Sep;373:738-748. doi: 10.1016/j.jconrel.2024.07.055. Epub 2024 Aug 2.
5
Tailoring micellar nanocarriers for pemetrexed in breast cancer: design, fabrication and evaluation.针对乳腺癌的培美曲塞定制胶束纳米载体：设计、制备与评价。
Nanomedicine (Lond). 2024;19(13):1145-1166. doi: 10.2217/nnm-2024-0013. Epub 2024 May 3.
6
Dual pH/redox-responsive hyperbranched polymeric nanocarriers with TME-trigger size shrinkage and charge reversible ability for amplified chemotherapy of breast cancer.具有 TME 触发尺寸收缩和电荷可逆能力的双 pH/氧化还原响应超支化聚合物纳米载体，用于乳腺癌的放大化疗。
Sci Rep. 2024 Apr 12;14(1):8567. doi: 10.1038/s41598-024-57296-4.
7
Optimization of lipid assisted polymeric nanoparticles for siRNA delivery and cancer immunotherapy.优化载脂聚合物纳米粒用于 siRNA 递送和癌症免疫治疗。
Biomater Sci. 2024 Apr 16;12(8):2057-2066. doi: 10.1039/d3bm02071a.
8
Context-Responsive Nanoparticle Derived from Synthetic Zwitterionic Ionizable Phospholipids in Targeted CRISPR/Cas9 Therapy for Basal-like Breast Cancer.基于合成两性离子可电离磷脂的响应性纳米颗粒在基底样乳腺癌靶向 CRISPR/Cas9 治疗中的应用
ACS Nano. 2024 Mar 26;18(12):9199-9220. doi: 10.1021/acsnano.4c01400. Epub 2024 Mar 11.
9
Advances with Lipid-Based Nanosystems for siRNA Delivery to Breast Cancers.基于脂质的纳米系统用于将小干扰RNA递送至乳腺癌的研究进展
Pharmaceuticals (Basel). 2023 Jul 6;16(7):970. doi: 10.3390/ph16070970.
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Recent advances in mesoporous silica nanoparticle-based targeted drug-delivery systems for cancer therapy.介孔硅纳米粒子为基础的靶向药物传递系统在癌症治疗中的最新进展。
Nanomedicine (Lond). 2022 Aug;17(18):1253-1279. doi: 10.2217/nnm-2022-0023. Epub 2022 Oct 17.