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先天性梅毒发病率上升：两例罕见但日益常见疾病骨科表现患者的病例系列及讨论

Congenital Syphilis on the Rise: A Case Series and Discussion of Two Patients With Orthopaedic Manifestations of a Rare but Increasingly Common Disease.

作者信息

Verheul Dirk, Farrar Jacob M, Kuester Victoria, Davey Shaunette

机构信息

From the Department of Orthopaedic Surgery, Medical College of Virginia, Virginia Commonwealth University Health System, Richmond, VA.

出版信息

J Am Acad Orthop Surg Glob Res Rev. 2024 Dec 6;8(12). doi: 10.5435/JAAOSGlobal-D-24-00221. eCollection 2024 Dec 1.

DOI:10.5435/JAAOSGlobal-D-24-00221
PMID:39656109
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11630935/
Abstract

Congenital syphilis is becoming increasingly common in the United States. Early identification and treatment are critical in preventing long-term sequelae, such as musculoskeletal deformity, and neurologic deficits. At our North American institution, two recent cases of congenital syphilis were identified primarily by their musculoskeletal manifestations. We describe these two cases and discuss the diagnostic challenges that they presented. In the setting of a rapid increase in the number of cases of congenital syphilis, this diagnosis is one of critical importance for orthopaedic surgeons to be familiar with. Identification can be difficult without high clinical suspicion, so increasing awareness is critical to ensuring timely diagnosis and treatment.

摘要

先天性梅毒在美国正变得越来越常见。早期识别和治疗对于预防长期后遗症（如肌肉骨骼畸形和神经功能缺损）至关重要。在我们这家北美机构，最近有两例先天性梅毒主要是通过其肌肉骨骼表现被发现的。我们描述这两例病例，并讨论它们所带来的诊断挑战。在先天性梅毒病例数迅速增加的背景下，这一诊断对于骨科医生来说是极其重要且需要熟悉的。如果临床怀疑度不高，识别可能会很困难，因此提高认识对于确保及时诊断和治疗至关重要。

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本文引用的文献

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Congenital Syphilis and the Orthopaedic Perspective: A Case Report.先天性梅毒与矫形科视角：病例报告。
JBJS Case Connect. 2024 May 3;14(2). doi: e24.00017. eCollection 2024 Apr 1.
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CDC Laboratory Recommendations for Syphilis Testing, United States, 2024.美国疾病预防控制中心 2024 年梅毒检测实验室推荐意见
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Congenital syphilis, the great mimicker, confused with non-accidental trauma.先天性梅毒，这个极具迷惑性的病症，常被误诊为非意外性创伤。
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