Hassani S, Lazem M, Jafari Z
Department of Audiology, School of Rehabilitation Sciences, Isfahan University of Medical Science, Isfahan, Iran.
Student Research Committee, Isfahan University of Medical Science, Isfahan, Iran.
J Laryngol Otol. 2021 Dec;135(12):1063-1068. doi: 10.1017/S002221512100267X. Epub 2021 Oct 1.
Otological complications are considered early symptoms of severe acute respiratory syndrome coronavirus-2; however, it is unknown how long these symptoms last and whether the virus leaves any hearing disorders post-recovery.
This prospective cohort study comprised 31 mild or moderate confirmed coronavirus disease 2019 patients and 26 age-matched control peers (21-50 years old). Patients were questioned about their otological symptoms, and their hearing status was assessed during one month post-diagnosis.
Patients showed a significantly higher rate of otological symptoms (hearing loss, ear fullness, ear pain, dizziness or vertigo, communication difficulties, and hyperacusis) versus the control group ( ≤ 0.022). The symptoms resolved early, between 2 and 8 days after their appearance. No significant differences were observed between the two groups in pure tone and extended high-frequency audiometry, transient evoked otoacoustic emissions, distortion product otoacoustic emissions, or auditory brainstem response following recovery.
The findings indicate that, in mild to moderate coronavirus disease 2019 cases, otological symptoms resolve within a week, and the virus has no lasting impact on the auditory system.
耳部并发症被认为是严重急性呼吸综合征冠状病毒2的早期症状;然而,这些症状会持续多久以及病毒在康复后是否会留下任何听力障碍尚不清楚。
这项前瞻性队列研究包括31例轻度或中度确诊的2019冠状病毒病患者和26名年龄匹配的对照者(21 - 50岁)。询问患者耳部症状,并在诊断后一个月内评估他们的听力状况。
与对照组相比,患者出现耳部症状(听力损失、耳闷、耳痛、头晕或眩晕、沟通困难和听觉过敏)的发生率显著更高(≤0.022)。症状在出现后的2至8天内早期缓解。康复后,两组在纯音和扩展高频听力测定、瞬态诱发耳声发射、畸变产物耳声发射或听觉脑干反应方面均未观察到显著差异。
研究结果表明,在轻度至中度的2019冠状病毒病病例中,耳部症状在一周内缓解,且该病毒对听觉系统没有持久影响。