Graduate Program in Nutrition, Universidade Federal de Pernambuco, Recife, PE, Brazil; Phenotypic Plasticity and Nutrition Studies Unit, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Phenotypic Plasticity and Nutrition Studies Unit, Universidade Federal de Pernambuco, Recife, PE, Brazil; Graduate Program in Nutrition, Physical Activity and Phenotypic Plasticity, Universidade Federal de Pernambuco, Vitória de Santo Antão, PE, Brazil.
Am J Otolaryngol. 2021 Mar-Apr;42(2):102889. doi: 10.1016/j.amjoto.2020.102889. Epub 2021 Jan 6.
The aim of the study was to conduct a systematic review of the literature to investigate the time of onset and duration of symptoms of loss of smell and taste in patients diagnosed with COVID-19.
Two independent authors performed a systematic review of the Medline/PubMed, SCOPUS, COCHRANE, Lilacs and Web of Science electronic databases. The time of onset and duration of symptoms were considered primary outcomes. The sex and age of individuals, the geographical location of the study, the prevalence of symptoms, other associated symptoms, associated comorbidities, and the impact on quality of life and eating habits were considered secondary outcomes.
Our search generated 17 articles. Many of the studies reported that the onset of anosmia and ageusia occurred 4 to 5 days after the manifestation of other symptoms of the infection and that these symptoms started to disappear after one week, with more significant improvements in the first two weeks.
The present study concludes that the onset of symptoms of loss of smell and taste, associated with COVID-19, occurs 4 to 5 days after other symptoms, and that these symptoms last from 7 to 14 days. Findings, however, varied and there is therefore a need for further studies to clarify the occurrence of these symptoms. This would help to provide early diagnosis and reduce contagion by the virus.
本研究旨在对文献进行系统回顾，以调查 COVID-19 患者嗅觉和味觉丧失症状的发病时间和持续时间。
两名独立作者对 Medline/PubMed、SCOPUS、COCHRANE、Lilacs 和 Web of Science 电子数据库进行了系统回顾。发病时间和症状持续时间被视为主要结局。个体的性别和年龄、研究地点、症状流行率、其他相关症状、相关合并症以及对生活质量和饮食习惯的影响被视为次要结局。
我们的搜索生成了 17 篇文章。许多研究报告称，嗅觉和味觉丧失的发病时间在感染其他症状出现后 4 至 5 天，这些症状在一周后开始消失，在前两周内有更显著的改善。
本研究得出的结论是，与 COVID-19 相关的嗅觉和味觉丧失症状在其他症状出现后 4 至 5 天发生，这些症状持续 7 至 14 天。然而，结果存在差异，因此需要进一步研究来阐明这些症状的发生情况。这将有助于提供早期诊断并减少病毒的传播。
