长效普萘洛尔治疗特发性震颤

Long-acting propranolol in essential tremor.

作者信息

Koller W C

出版信息

Neurology. 1985 Jan;35(1):108-10. doi: 10.1212/wnl.35.1.108.

DOI:10.1212/wnl.35.1.108

Abstract

Long-acting propranolol (propranolol-LA) was compared with propranolol in divided doses in 18 patients with essential tremor. Three patients were unresponsive to both preparations. Propranolol-LA was preferred by 87% of patients for ease of administration and by 67% for tremor control. Propranolol-LA provided similar (53%), and in some patients greater (47%), reduction of tremor amplitude than divided dosing. Propranolol-LA should be a useful drug in essential tremor.

摘要

将长效普萘洛尔（普萘洛尔-LA）与分剂量普萘洛尔在18例特发性震颤患者中进行了比较。3例患者对两种制剂均无反应。87%的患者因给药方便而更喜欢普萘洛尔-LA，67%的患者因震颤控制效果而更喜欢它。与分剂量给药相比，普萘洛尔-LA使震颤幅度降低程度相似（53%），在一些患者中降低程度更大（47%）。普萘洛尔-LA应是治疗特发性震颤的一种有用药物。