Department of Neurology, Parkinson Research Foundation, James A. Haley Veterans Administration Hospital, University of South Florida, Tampa, FL, USA.
Neuropsychiatr Dis Treat. 2010 Sep 7;6:401-8. doi: 10.2147/ndt.s4795.
Essential tremor (ET) is one of the most common movement disorders in the world. Despite this, only one medication (propranolol) is approved by the Food and Drug Administration (FDA) to treat it. Fortunately, recent studies have identified some additional medications as treatment of ET. Surgical procedures, such as deep brain stimulation of the ventral intermediate nucleus of the thalamus, offer treatment for refractory tremor. The epidemiology, pathogenesis, and medical and surgical treatment of ET will be discussed in this paper.
特发性震颤(ET)是世界上最常见的运动障碍之一。尽管如此,只有一种药物(普萘洛尔)被美国食品和药物管理局(FDA)批准用于治疗该病。幸运的是,最近的研究已经确定了一些其他药物可用于治疗 ET。手术程序,如丘脑腹侧中间核的深部脑刺激,为难治性震颤提供了治疗方法。本文将讨论 ET 的流行病学、发病机制以及医学和手术治疗。