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双侧经典型三叉神经痛的即刻连续微血管减压术

Immediate consecutive microvascular decompression for bilateral classical trigeminal neuralgia.

作者信息

Segura-Lozano Mauro Alberto, Del Real-Gallegos Mario Alexis, Mendoza-Lemus Pedro, Carranza-Rentería Octavio, Torres-Torres Yael Rodrigo, González-Silva Alejandro, Santoyo-Pantoja Arturo, Munguía-Rodríguez Aarón Giovanni

机构信息

Neurología Segura Medical Center, Hospital Angeles Morelia, Morelia, Mexico.

出版信息

Front Neurol. 2024 Nov 26;15:1496656. doi: 10.3389/fneur.2024.1496656. eCollection 2024.

Abstract

BACKGROUND

Classical trigeminal neuralgia (TN) is characterized by sudden, severe facial pain, typically resulting from a neurovascular conflict affecting the trigeminal nerve. In rare cases, both nerves are affected simultaneously causing bilateral TN (BTN), increasing the complexity of the treatment. Microvascular decompression (MVD) is a well-established treatment for TN; however, the experience with immediate consecutive bilateral MVD procedures is limited and requires further evaluation.

OBJECTIVE

To evaluate the safety and efficacy of immediate consecutive bilateral MVD in patients with severe BTN compared to non-consecutive bilateral MVD procedures.

METHODS

A retrospective analysis was conducted on 15 patients with BTN who underwent bilateral MVD. The data on clinical presentation, surgical technique, perioperative findings, complications, and follow-up outcomes of three cases of BTN treated with consecutive bilateral MVD surgeries were analyzed and compared to 12 who received separated procedures. Moreover, a detailed presentation of the three cases of consecutive MVD is provided to illustrate clinical decision-making, surgical nuances, and individual outcomes.

RESULTS

Both groups achieved significant pain relief ( < 0.001) without notable differences in Barrow Neurological Institute (BNI) pain intensity score ( = 0.305), indicating that both approaches were equally effective. The consecutive MVD group experienced a shorter total surgical duration ( = 0.025), while postoperative complications were comparable ( = 0.077), mostly transient with no major adverse events or mortality. At the last follow-up, the patients remained pain-free without recurrence of TN symptoms.

CONCLUSION

Consecutive bilateral MVD is a safe and effective option, comparable to non-consecutive procedures for treating BTN. This approach provides a viable alternative for patients with severe bilateral symptoms or when medical constraints limit the possibility of two separate surgeries. Further studies with larger cohorts and extended follow-up periods are needed to support these results.

摘要

背景

经典三叉神经痛(TN)的特征是突发的、严重的面部疼痛,通常由影响三叉神经的神经血管冲突引起。在罕见情况下,双侧神经会同时受到影响,导致双侧TN(BTN),增加了治疗的复杂性。微血管减压术(MVD)是一种成熟的TN治疗方法;然而,连续立即进行双侧MVD手术的经验有限,需要进一步评估。

目的

与非连续双侧MVD手术相比,评估连续立即双侧MVD治疗重度BTN患者的安全性和有效性。

方法

对15例接受双侧MVD的BTN患者进行回顾性分析。分析了连续双侧MVD手术治疗的3例BTN患者的临床表现、手术技术、围手术期发现、并发症和随访结果,并与12例接受非连续手术的患者进行比较。此外,还详细介绍了3例连续MVD病例,以说明临床决策、手术细节和个体结果。

结果

两组均实现了显著的疼痛缓解(<0.001),在巴罗神经学研究所(BNI)疼痛强度评分方面无显著差异(=0.305),表明两种方法同样有效。连续MVD组的总手术时间较短(=0.025),而术后并发症相当(=0.077),大多为短暂性,无重大不良事件或死亡。在最后一次随访时,患者仍无疼痛,TN症状未复发。

结论

连续双侧MVD是一种安全有效的选择,与非连续手术治疗BTN相当。这种方法为有严重双侧症状的患者或因医疗限制无法进行两次单独手术的患者提供了一种可行的替代方案。需要进行更大样本量和更长随访期的进一步研究来支持这些结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88df/11628375/c1d999f0b44a/fneur-15-1496656-g001.jpg

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