Stålhammar Gustav, Vishnevskia-Dai Vicktoria, Verdijk Robert M, Moulin Alexandre
Department of Clinical Neuroscience, Division of Eye and Vision, Karolinska Institutet, Stockholm, Sweden.
Ocular Oncology Service, St. Erik Eye Hospital, Stockholm, Sweden.
Ocul Oncol Pathol. 2024 Dec;10(4):197-205. doi: 10.1159/000541016. Epub 2024 Aug 27.
Clear evidence for the best clinical management of uveal melanoma is lacking in some areas. Therefore, reports on expert opinions in the field can be valuable.
A questionnaire comprising 10 questions was distributed to potential participants of the 58th Ophthalmic Oncology Group Meeting in Stockholm, Sweden, in June 2024.
Among 34 respondents, 13 (38%) had >20 years of postresidency experience in ophthalmic oncology. The maximum recommended tumor thickness for ruthenium-106 plaque brachytherapy was 5.7 mm (SD 1.1). Twenty-three respondents (68%) indicated that radiological surveillance for metastatic disease should be conducted irrespective of primary tumor characteristics. A majority (74%) would treat a lesion with a 6 mm diameter and 1.5 mm thickness without waiting for evidence of growth if sufficient risk factors were present. Most experts did not currently recommend sampling of circulating tumor DNA or circulating tumor cells. There were no significant differences in responses based on the experience of respondents (≤20 vs. >20 years) or their annual volume of new cases (≤50 vs. >50).
This article reports the opinions of 34 experts in ophthalmic oncology on various contemporary topics in uveal melanoma. The responses illustrate both agreements and differences in opinions among experts.
在葡萄膜黑色素瘤的最佳临床管理方面，某些领域缺乏明确的证据。因此，该领域的专家意见报告可能很有价值。
2024年6月，向瑞典斯德哥尔摩第58届眼科肿瘤学组会议的潜在参与者发放了一份包含10个问题的问卷。
在34名受访者中，13人（38%）在眼科肿瘤学方面有超过20年的住院后经验。钌-106斑块近距离放射治疗的最大推荐肿瘤厚度为5.7毫米（标准差1.1）。23名受访者（68%）表示，无论原发性肿瘤特征如何，都应进行转移性疾病的放射学监测。如果存在足够的风险因素，大多数人（74%）会在不等待生长证据的情况下治疗直径6毫米、厚度1.5毫米的病变。目前大多数专家不建议对循环肿瘤DNA或循环肿瘤细胞进行采样。根据受访者的经验（≤20年与>20年）或他们每年的新病例数量（≤50例与>50例），回答没有显著差异。
本文报告了34位眼科肿瘤学专家对葡萄膜黑色素瘤各种当代主题的意见。这些回答显示了专家之间意见的一致和分歧。
