Houston G A, Files J C, Morrison F S
South Med J. 1985 Jan;78(1):69-70. doi: 10.1097/00007611-198501000-00019.
We have described a 22-year-old black man with pernicious anemia, classically considered a disease of middle-aged and elderly Northern Europeans. It is considered rare in non-caucasians and children. The majority of very young patients have been considered to have the congenital form of pernicious and anemia, characterized by absence of intrinsic factor with normal gastric mucosa and acid production. We have seen no patients with this type of the disease. Furthermore, all five patients under 25 years of age and eight of nine under 35 were black. We found no racial difference in the incidence of pernicious anemia, but we believe it may occur at a younger age in black patients.
我们描述了一名患有恶性贫血的22岁黑人男性，恶性贫血传统上被认为是北欧中年和老年人群的疾病。在非白种人和儿童中被认为较为罕见。大多数非常年轻的患者被认为患有先天性恶性贫血，其特征是胃黏膜和胃酸分泌正常但缺乏内因子。我们尚未见过这类疾病的患者。此外，所有5名25岁以下的患者以及9名35岁以下患者中的8名都是黑人。我们发现恶性贫血的发病率没有种族差异，但我们认为它在黑人患者中可能发病年龄更小。
