Carmel R, Johnson C S, Weiner J M
Department of Medicine, University of Southern California, Los Angeles 90033.
Arch Intern Med. 1987 Nov;147(11):1995-6.
Pernicious anemia is widely regarded as a disease of the elderly. However, it is expressed differently in black women, among the most striking differences being their younger age at presentation of the disease compared with whites. We now compared 92 Latin-American patients with 115 white and 100 black patients to see if similar age differences occur in other racial groups. Latin-American men and women were both significantly younger than white men and women, and were similar in age to blacks. Only 21% of Latin-American patients were 70 years of age or older, compared with 49% of whites. It is apparent that pernicious anemia is indeed predominantly a disease of the elderly in whites but that this is not the case in other racial groups.
恶性贫血被广泛认为是一种老年疾病。然而，它在黑人女性中的表现有所不同，最显著的差异之一是与白人相比，她们患这种疾病时的年龄更小。我们现在将92名拉丁裔患者与115名白人和100名黑人患者进行比较，以观察其他种族群体中是否存在类似的年龄差异。拉丁裔男性和女性的年龄均显著低于白种男性和女性，且与黑人的年龄相近。只有21%的拉丁裔患者年龄在70岁及以上，而白人患者这一比例为49%。显然，恶性贫血在白人中确实主要是一种老年疾病，但在其他种族群体中并非如此。
