Seddon J M, Baranetsky N, Van Boxel P J
Urology. 1985 Jan;25(1):1-7. doi: 10.1016/0090-4295(85)90552-7.
A series of eleven adrenal tumors is presented. Only one of the adrenal tumors showed evidence of endocrine function while eight tumors were incidentally discovered during radiologic evaluations. Surgical exploration was performed in all cases as the final diagnostic measure. There were four malignancies, three nonfunctioning carcinomas, and one neuroblastoma. Two of the four malignancies were discovered incidentally on radiologic evaluation and were considered preoperatively to be benign cystic lesions by radiographic criteria. One benign adrenal hamartoma was diagnosed preoperatively as an adrenal carcinoma. In view of the questionable accuracy of radiologic diagnosis of adrenal masses and the well-documented difficulty in differentiating adrenal adenomas from carcinomas on histologic grounds, consideration should be given to the surgical exploration and excision of all adrenal masses discovered incidentally.
本文报告了一系列11例肾上腺肿瘤。只有1例肾上腺肿瘤显示有内分泌功能证据,而8例肿瘤是在影像学评估时偶然发现的。所有病例均进行了手术探查作为最终诊断措施。其中有4例恶性肿瘤,3例无功能癌和1例神经母细胞瘤。4例恶性肿瘤中有2例是在影像学评估时偶然发现的,术前根据影像学标准被认为是良性囊性病变。1例良性肾上腺错构瘤术前被诊断为肾上腺癌。鉴于肾上腺肿块影像学诊断的准确性存疑,以及有充分文献记载的在组织学上难以区分肾上腺腺瘤与癌,对于偶然发现的所有肾上腺肿块,均应考虑手术探查并切除。