Perin Maria Luiza Costabeber, Silva Letícia Souza Mata da, Duarte Maysa Lannes, Primo Laura Guimarães
Postgraduate Student in Pediatric Dentistry At Universidad Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Postdoctoral Associate Possessor of The Postgraduate Program in Dentistry, Universiade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Lasers Med Sci. 2024 Dec 12;39(1):292. doi: 10.1007/s10103-024-04250-5.
The objective of this study was to identify, describe and synthesize the data published about the effectiveness of antimicrobial photodynamic therapy (aPDT) in the pulpectomy of primary teeth. A search was conducted in six electronic databases and the gray literature in June and July 2023, without restrictions on language or date of publication. The search strategy included indexed terms (MeSH terms) and your synonyms. Clinical trials, in vitro studies, case reports and retrospective studies that used photodynamic therapy in primary teeth pulpectomies were considered eligible. Among the 1,674 articles retrieved, 15 were included, published between 2014 and 2022, comprising six in vitro studies, five clinical trials, and four case reports. The sample consisted of children aged 2 to 8 years of both sexes, and included 1 to 62 teeth, mostly anterior. In two in vitro studies, the sample was taken from root canals. Most studies used a diode laser, methylene blue, and optical fiber. The pre-irradiation time ranged from 1 to 5 min. All protocols demonstrated microbial reduction before and after using aPDT, with no statistical difference among the groups. Furthermore, six studies demonstrated treatment success. Despite the divergence in methodology and protocols, aPDT is an effective method for reducing microorganisms, and is a promising adjunct treatment in primary teeth pulpectomies.
本研究的目的是识别、描述和综合已发表的关于抗菌光动力疗法（aPDT）在乳牙牙髓摘除术中有效性的数据。于2023年6月和7月在六个电子数据库及灰色文献中进行了检索，对语言和出版日期无限制。检索策略包括索引词（医学主题词）及其同义词。在乳牙牙髓摘除术中使用光动力疗法的临床试验、体外研究、病例报告和回顾性研究被视为符合条件。在检索到的1674篇文章中，纳入了15篇，发表于2014年至2022年之间，包括六项体外研究、五项临床试验和四项病例报告。样本包括2至8岁的男女儿童，包含1至62颗牙齿，大多为前牙。在两项体外研究中，样本取自根管。大多数研究使用二极管激光、亚甲蓝和光纤。照射前时间为1至5分钟。所有方案在使用aPDT前后均显示出微生物减少，各组之间无统计学差异。此外，六项研究显示治疗成功。尽管方法和方案存在差异，但aPDT是一种减少微生物的有效方法，并且是乳牙牙髓摘除术中一种有前景的辅助治疗方法。
