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耳廓螺旋部多形性皮肤肉瘤

Pleomorphic dermal sarcoma of the auricular helix.

作者信息

Dekhou Antonio, Bond Laurel, Bryant Stephanie M, Silverman Dustin A

机构信息

Department of Otolaryngology, Head & Neck Surgery, University of Cincinnati Medical Center, Cincinnati, OH, United States.

Department of Pathology, University of Cincinnati Medical Center, Cincinnati, OH, United States.

出版信息

J Surg Case Rep. 2024 Dec 11;2024(12):rjae781. doi: 10.1093/jscr/rjae781. eCollection 2024 Dec.

DOI:10.1093/jscr/rjae781
PMID:39664276
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11632825/
Abstract

Cutaneous malignancies of the head and neck are common; however, superficial sarcomas of the head and neck are relatively rare. We present a 71-year-old unhoused gentleman with challenging access to medical care and poor health literacy who presented with a large, isolated, pedunculated mass of the left auricular helix. Preoperative biopsy was compatible with pleomorphic dermal sarcoma (PDS). The patient subsequently underwent definitive surgical resection with partial auriculectomy and bilateral advancement flap closure. Final pathology confirmed the diagnosis of PDS. Given the rarity of PDS of the ear, we describe a challenging case presentation, diagnosis, and management in an unhoused patient.

摘要

头颈部皮肤恶性肿瘤很常见;然而,头颈部浅表肉瘤相对罕见。我们报告一位71岁的无家可归男性,他获得医疗护理困难且健康素养差,因左耳廓螺旋部出现一个巨大、孤立、带蒂肿物前来就诊。术前活检结果符合多形性皮肤肉瘤(PDS)。患者随后接受了确定性手术切除,包括部分耳廓切除术和双侧推进皮瓣闭合术。最终病理确诊为PDS。鉴于耳部PDS的罕见性,我们描述了一位无家可归患者具有挑战性的病例表现、诊断及治疗过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/403d/11632825/220e773abd34/rjae781f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/403d/11632825/5a94a9d405b3/rjae781f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/403d/11632825/b463e24f6fb0/rjae781f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/403d/11632825/6d84836db6c5/rjae781f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/403d/11632825/220e773abd34/rjae781f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/403d/11632825/5a94a9d405b3/rjae781f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/403d/11632825/b463e24f6fb0/rjae781f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/403d/11632825/6d84836db6c5/rjae781f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/403d/11632825/220e773abd34/rjae781f4.jpg

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本文引用的文献

1
Transoral Excision of a Hypopharyngeal Liposarcoma.经口切除下咽脂肪肉瘤。
Laryngoscope. 2024 Nov;134(11):4688-4690. doi: 10.1002/lary.31553. Epub 2024 Jun 1.
2
Pleomorphic Dermal Sarcoma.多形性皮肤肉瘤。
Surg Pathol Clin. 2024 Mar;17(1):153-158. doi: 10.1016/j.path.2023.06.007. Epub 2023 Aug 5.
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Pleomorphic dermal sarcoma: it might be rare but it exists.多形性皮肤肉瘤:它可能罕见,但确实存在。
J Surg Case Rep. 2023 Aug 4;2023(8):rjad374. doi: 10.1093/jscr/rjad374. eCollection 2023 Aug.
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Pleomorphic dermal sarcoma: a clinical and histological review of 49 cases.多形性皮肤肉瘤:49 例临床和组织学回顾。
Br J Oral Maxillofac Surg. 2021 May;59(4):460-465. doi: 10.1016/j.bjoms.2020.09.007. Epub 2020 Sep 11.
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Management of pleomorphic dermal sarcoma.多形性皮肤肉瘤的管理
ANZ J Surg. 2020 Nov;90(11):2322-2324. doi: 10.1111/ans.15909. Epub 2020 Apr 27.
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Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma: Updates on Classification and Management.非典型纤维黄色瘤和多形性真皮肉瘤:分类和治疗的最新进展。
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Cutaneous sarcomas.皮肤肉瘤
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8
Study of Epithelial to Mesenchymal Transition in Atypical Fibroxanthoma and Undifferentiated Pleomorphic Sarcoma to Discern an Epithelial Origin.非典型纤维黄色瘤和未分化多形性肉瘤中上皮-间质转化的研究以辨别上皮起源
Am J Dermatopathol. 2016 Apr;38(4):270-7. doi: 10.1097/DAD.0000000000000396.
9
TERT promoter mutations are frequent in atypical fibroxanthomas and pleomorphic dermal sarcomas.TERT 启动子突变在非典型纤维黄色瘤和多形性真皮肉瘤中很常见。
Mod Pathol. 2014 Apr;27(4):502-8. doi: 10.1038/modpathol.2013.168. Epub 2013 Sep 13.
10
Pleomorphic dermal sarcoma: adverse histologic features predict aggressive behavior and allow distinction from atypical fibroxanthoma.多形性皮肤肉瘤:不良组织学特征预示侵袭性行为,并可与非典型纤维黄色瘤相区别。
Am J Surg Pathol. 2012 Sep;36(9):1317-26. doi: 10.1097/PAS.0b013e31825359e1.