Yun Young Bin, Kim Young Gun, Pak Min Gyoung, Kim Sangjun
Department of Otorhinolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Republic of Korea.
Department of Pathology, Dong-A University College of Medicine, Busan, Republic of Korea.
J Rhinol. 2022 Nov;29(3):176-181. doi: 10.18787/jr.2022.00415. Epub 2022 Nov 30.
Nasal type natural killer/T-cell lymphoma (NNKTL) is a rare and aggressive subtype of non-Hodgkin lymphoma originating from a natural killer cell or γδ T cell infected by the Epstein-Barr virus. It usually invades the aerodigestive tract and can rapidly destroy the paranasal sinus, hard palate, and central nervous system. NNKTL is often mistaken for benign conditions such as chronic hypertrophic rhinosinusitis or mucosal inflammatory change, as endoscopic findings of NNKTL presenting nasal mucosal hypertrophy are similar to endoscopic findings for these abovementioned benign conditions. Here, the authors report the diagnosis and examination of NNKTL in a 58-year-old male patient who visited our clinic for nasal cavity discomfort after he underwent a dacryocystorhinostomy to treat dacryocystitis.
鼻型自然杀伤细胞/T细胞淋巴瘤(NNKTL)是一种罕见且侵袭性强的非霍奇金淋巴瘤亚型,起源于感染了爱泼斯坦-巴尔病毒的自然杀伤细胞或γδT细胞。它通常侵犯上呼吸道和消化道,可迅速破坏鼻窦、硬腭及中枢神经系统。NNKTL常被误诊为慢性肥厚性鼻窦炎或黏膜炎症性改变等良性疾病,因为表现为鼻黏膜肥厚的NNKTL的内镜检查结果与上述良性疾病的内镜检查结果相似。在此,作者报告了一名58岁男性患者NNKTL的诊断及检查情况,该患者因患泪囊炎接受泪囊鼻腔吻合术后因鼻腔不适前来我院就诊。