Kim Ji-Sun, Lee Dong Chang
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
J Rhinol. 2023 Jul;30(2):57-61. doi: 10.18787/jr.2023.00017. Epub 2023 Jul 28.
Chronic rhinosinusitis (CRS) is a relatively common inflammatory disease of the nasal and paranasal sinus mucosa. Several epidemiological studies have established an association between particulate matter (PM) and CRS. Based on those data, PM has emerged as an important environmental factor in the development of CRS. Recent research has investigated the mechanisms and treatment options for CRS caused by PM through cellular experimentation. Therefore, the authors would like to explain the definition of PM, present research investigating the relationship between PM and CRS, and summarize the involved mechanisms reported to date.
慢性鼻-鼻窦炎（CRS）是一种相对常见的鼻腔和鼻窦黏膜炎症性疾病。多项流行病学研究已证实颗粒物（PM）与CRS之间存在关联。基于这些数据，PM已成为CRS发病过程中的一个重要环境因素。近期研究通过细胞实验对PM所致CRS的机制及治疗方案进行了探究。因此，作者将解释PM的定义，介绍有关PM与CRS关系的研究，并总结迄今报道的相关机制。
