Seo Myeonggu, Park Ji-Hwan, Kim Sung-Dong, Choi Kyung Un, Cho Kyu-Sup
Department of Otorhinolaryngology and Biomedical Research Institute, Pusan National University School of Medicine, Pusan National University Hospital, Busan, Republic of Korea.
Department of Pathology, Pusan National University School of Medicine, Pusan National University Hospital, Busan, Republic of Korea.
J Rhinol. 2023 Nov;30(3):173-176. doi: 10.18787/jr.2023.00032. Epub 2023 Nov 27.
Plasmacytoma is a rare hematolymphoid malignancy. The three types of plasmacytoma, according to clinical features and morphological characteristics, include solitary bone plasmacytoma, extramedullary plasmacytoma (EMP), and multiple myeloma (MM). Although EMP of the head and neck region accounts for approximately 3% of all plasma cell tumors, the involvement of both paranasal sinuses is extremely rare. Herein, we describe a rare case of EMP involving both maxillary sinuses in a 73-year-old male patient who had achieved complete remission from MM following chemotherapy 2 years ago. The EMP was treated successfully with radiotherapy.
浆细胞瘤是一种罕见的血液淋巴系统恶性肿瘤。根据临床特征和形态学特点,浆细胞瘤可分为三种类型,即孤立性骨浆细胞瘤、髓外浆细胞瘤(EMP)和多发性骨髓瘤(MM)。虽然头颈部区域的EMP约占所有浆细胞肿瘤的3%,但双侧鼻窦受累极为罕见。在此,我们描述了一例罕见的EMP病例,该病例发生在一名73岁男性患者身上,其双侧上颌窦均受累,该患者两年前化疗后MM已完全缓解。该EMP通过放疗成功治愈。