Departamento de Radiología, Facultad de Medicina de la Universidad Ondokuz Mayis, Samsun, Turkey.
Departamento de Radiología, Facultad de Medicina de la Universidad Ondokuz Mayis, Samsun, Turkey.
Radiologia (Engl Ed). 2022 Jan-Feb;64(1):69-73. doi: 10.1016/j.rxeng.2020.07.007.
Extramedullary plasmacytoma (EMP) is a plasma cell neoplasm of soft tissue without bone marrow involvement or other systemic characteristics of multiple myeloma. Approximately 80%-90% of EMPs involve the head and neck region, especially in the nasal cavity, paranasal sinuses, tonsillar fossa, and oral cavity. An EMP of the larynx is extremely rare and is a locally destructive lesion without systemic spread. Clinical features vary depending on the tumor location. A diagnosis is established by histopathology, immunohistochemistry, and a systemic survey to exclude systemic plasma cell proliferative diseases. Extramedullary plasmacytomas are highly radiosensitive and radiotherapy is therefore used as a treatment. In this study, we report on a rare case of EMP of the larynx evaluated with computed tomography and present histopathologic findings for a 74-year-old female patient.
髓外浆细胞瘤（EMP）是一种软组织浆细胞肿瘤，不伴有骨髓累及或多发性骨髓瘤的其他全身特征。约 80%-90%的 EMP 发生于头颈部，尤其是鼻腔、鼻窦、扁桃体窝和口腔。喉的 EMP 极为罕见，为局部破坏性病变，无全身播散。临床特征取决于肿瘤部位。诊断依据组织病理学、免疫组化和全身检查，以排除全身浆细胞增殖性疾病。髓外浆细胞瘤对放射线高度敏感，因此采用放疗作为治疗方法。本研究报告了一例经计算机断层扫描评估的罕见喉 EMP 病例，并展示了一位 74 岁女性患者的组织病理学发现。
