Prevalence and Risk Factors of Infection in Elderly Patients With Upper Gastrointestinal Symptoms in Vietnam.

BACKGROUND AND AIM

infection is a major cause of peptic ulcer disease and gastric cancer. Limited data exist on prevalence and risk factors of infection among elderly individuals in Vietnam. This study aimed to determine the prevalence and associated risk factors of infection in elderly Vietnamese patients with upper gastrointestinal symptoms.

METHODS

A cross-sectional study was conducted on patients aged ≥ 60 years with upper gastrointestinal symptoms who underwent endoscopy. The exclusion criteria included recent antibiotic or proton pump inhibitor use, prior eradication, or upper gastrointestinal surgery. Data on demographics, hygiene, diet, and history were collected through structured questionnaires. was diagnosed by a rapid urease test. Logistic regression was used to analyze risk factors.

RESULTS

Of 406 participants (mean age 65.4 ± 4.5 years, male-to-female ratio 1:2), prevalence was 55.6%. The risk factors for infection included infrequent tooth brushing (OR 18.14, 95% CI 3.94-83.55), overweight/obesity (OR 5.82, 95% CI 3.44-9.88), spicy food consumption (OR 5.18, 95% CI 2.74-9.79), a family history of upper gastrointestinal symptoms (OR 3.15, 95% CI 1.84-5.39), and cat ownership (OR 2.01, 95% CI 1.10-3.68). The vegetarian diet was protective (OR 0.04, 95% CI 0.01-0.18).

CONCLUSIONS

prevalence in elderly Vietnamese is high, with risk factors including poor hygiene, obesity, spicy food, family history, and cat ownership. A vegetarian diet may be protective.