Ho Loi N, Quach Duc T
Faculty of Medicine University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City Vietnam.
Outpatient Department University Medical Center Ho Chi Minh City Ho Chi Minh City Vietnam.
JGH Open. 2024 Dec 11;8(12):e70074. doi: 10.1002/jgh3.70074. eCollection 2024 Dec.
infection is a major cause of peptic ulcer disease and gastric cancer. Limited data exist on prevalence and risk factors of infection among elderly individuals in Vietnam. This study aimed to determine the prevalence and associated risk factors of infection in elderly Vietnamese patients with upper gastrointestinal symptoms.
A cross-sectional study was conducted on patients aged ≥ 60 years with upper gastrointestinal symptoms who underwent endoscopy. The exclusion criteria included recent antibiotic or proton pump inhibitor use, prior eradication, or upper gastrointestinal surgery. Data on demographics, hygiene, diet, and history were collected through structured questionnaires. was diagnosed by a rapid urease test. Logistic regression was used to analyze risk factors.
Of 406 participants (mean age 65.4 ± 4.5 years, male-to-female ratio 1:2), prevalence was 55.6%. The risk factors for infection included infrequent tooth brushing (OR 18.14, 95% CI 3.94-83.55), overweight/obesity (OR 5.82, 95% CI 3.44-9.88), spicy food consumption (OR 5.18, 95% CI 2.74-9.79), a family history of upper gastrointestinal symptoms (OR 3.15, 95% CI 1.84-5.39), and cat ownership (OR 2.01, 95% CI 1.10-3.68). The vegetarian diet was protective (OR 0.04, 95% CI 0.01-0.18).
prevalence in elderly Vietnamese is high, with risk factors including poor hygiene, obesity, spicy food, family history, and cat ownership. A vegetarian diet may be protective.
感染是消化性溃疡疾病和胃癌的主要病因。越南老年人群中感染的患病率及危险因素的数据有限。本研究旨在确定越南有上消化道症状的老年患者中感染的患病率及相关危险因素。
对年龄≥60岁且有上消化道症状并接受内镜检查的患者进行了一项横断面研究。排除标准包括近期使用抗生素或质子泵抑制剂、既往根除治疗或上消化道手术。通过结构化问卷收集人口统计学、卫生、饮食和病史数据。通过快速尿素酶试验诊断感染。采用逻辑回归分析危险因素。
406名参与者（平均年龄65.4±4.5岁，男女比例1:2）中，感染患病率为55.6%。感染的危险因素包括刷牙不频繁（比值比18.14，95%置信区间3.94 - 83.55）、超重/肥胖（比值比5.82，95%置信区间3.44 - 9.88）、食用辛辣食物（比值比5.18，95%置信区间2.74 - 9.79）、上消化道症状家族史（比值比3.15，95%置信区间1.84 - 5.39）和养猫（比值比2.01，95%置信区间1.10 - 3.68）。素食饮食具有保护作用（比值比0.04，95%置信区间0.01 - 0.18）。
越南老年人中感染患病率较高，危险因素包括卫生状况差、肥胖、辛辣食物、家族史和养猫。素食饮食可能具有保护作用。
