Yu Adam C, Chan Airiss R, Chow Eunice Y
Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Division of Dermatology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
SAGE Open Med Case Rep. 2024 Dec 11;12:2050313X241304881. doi: 10.1177/2050313X241304881. eCollection 2024.
Leprosy remains a persistent health challenge in endemic regions with cases rising in non-endemic regions such as North America. Patients with leprosy present with a variety of symptoms including limited skin lesions in tuberculoid leprosy to extensive lesions and high bacterial proliferation in lepromatous leprosy. This case report details a 77-year-old Canadian man of South Asian descent with lepromatous leprosy and Lucio's phenomenon in Western Canada. The patient exhibited widespread retiform purpura on the limbs with localized ulcerations, erosions, and necrosis on the left hand and feet, peripheral neuropathy, and digit shortening. Histopathological examination and PCR confirmed . Management involved a 24-month multidrug therapy, leading to significant symptom reduction. This report highlights the diagnostic challenges of leprosy in non-endemic regions and the importance of a multidisciplinary approach for accurate diagnosis and treatment.
在麻风病流行地区，麻风病仍然是一个持续存在的健康挑战，而且在北美等非流行地区病例也在增加。麻风病患者会出现多种症状，从结核样型麻风的局限性皮肤损害到瘤型麻风的广泛损害和高细菌增殖。本病例报告详细介绍了一名77岁的南亚裔加拿大男子，他在加拿大西部患瘤型麻风及卢西奥现象。患者四肢出现广泛的网状紫癜，左手和足部有局部溃疡、糜烂和坏死，伴有周围神经病变和手指缩短。组织病理学检查和聚合酶链反应证实了诊断。治疗采用了为期24个月的多药疗法，症状显著减轻。本报告强调了非流行地区麻风病的诊断挑战以及多学科方法对于准确诊断和治疗的重要性。
