Barbara L, Belsasso E, Blasi A, Caenazzo E, Di Febo G, Di Mario F, Giorgi-Conciato M, Marletta F, Miglioli M, Petrillo M, Salvagnini M, Scalabrin G
Scand J Gastroenterol Suppl. 1979;57:21-4.
Pirenzepine (PRZ) 75 mg/day for 1 week followed by 50 mg/day for 3 weeks did not show a good activity in gastric ulcer healing in comparison to carbenoxolone (CB) (300 mg/day for 1 week followed by 200 mg/day for 3 weeks). The tolerability of PRZ seemed to be better than that of CB. The increase in the daily dose of PRZ to 100 mg/day for 4 weeks led to better results in the patients who have completed satisfactorily the treatment up to now. PRZ's tolerability was greater than CB's. The results of this study are preliminary to further trial.
与甘珀酸（CB）（第1周300毫克/天，随后3周200毫克/天）相比，哌仑西平（PRZ）75毫克/天服用1周，随后50毫克/天服用3周，在胃溃疡愈合方面未显示出良好疗效。PRZ的耐受性似乎优于CB。将PRZ的日剂量增加至100毫克/天并持续4周，对于目前已圆满完成治疗的患者产生了更好的效果。PRZ的耐受性高于CB。本研究结果尚需进一步试验验证。
