Huerta Alicia, Salim Ella, Bonilla Haley V, Miller Sarah E, Assoumou Sabrina A
From the Boston University Chobanian & Avedisian School of Medicine, Boston, MA (AH); Section of Infectious Diseases, Boston Medical Center, Boston, MA (ES, HVB, SEM, SAA); and Section of Infectious Diseases, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA (SAA).
J Addict Med. 2024 Dec 12. doi: 10.1097/ADM.0000000000001432.
The US overdose crisis is driving a surge in HIV diagnoses among persons who inject drugs (PWID). Innovative approaches are needed to address this increase in cases. Although HIV self-testing (HIVST) was hailed as a potential "game-changer" upon initial approval by the Food and Drug Administration over a decade ago, this convenient testing modality has not reached its full potential to impact the HIV epidemic. Nevertheless, lessons regarding self-testing for infectious diseases from the COVID-19 pandemic present an opportunity to increase HIVST uptake and reach current US goals of Ending the HIV Epidemic (EHE) by 2030. In this commentary, we first discuss facilitators and barriers of HIVST for PWID. We then explore how lessons regarding self-testing during the COVID-19 pandemic can allow us to realize the potential of HIVST for PWID. We conclude by suggesting the future utilization of HIVST to address 2 EHE pillars, rapid diagnosis of HIV cases and cluster identification.
美国的药物过量危机导致注射吸毒者（PWID）中的艾滋病毒诊断病例激增。需要创新方法来应对病例的增加。尽管十多年前美国食品药品监督管理局最初批准艾滋病毒自我检测（HIVST）时，它被誉为潜在的“变革者”，但这种便捷的检测方式尚未充分发挥其对艾滋病毒流行的影响潜力。然而，新冠疫情中传染病自我检测的经验教训为提高HIVST的使用率以及实现美国到2030年“终结艾滋病毒流行”（EHE）的当前目标提供了契机。在这篇评论中，我们首先讨论PWID进行HIVST的促进因素和障碍。然后，我们探讨新冠疫情期间自我检测的经验教训如何使我们能够实现HIVST对PWID的潜力。我们最后建议未来利用HIVST来实现EHE的两个支柱目标，即艾滋病毒病例的快速诊断和聚集性识别。
