Priego-Jiménez Susana, Lucerón-Lucas-Torres Maribel, Lorenzo-García Patricia, González-Molinero Marta, Bermejo-Cantarero Alberto, Álvarez-Bueno Celia
Hospital Virgen de la Luz. C/ Hermandad de Donantes de Sangre, 1. 16002. Cuenca, Spain.
Health and Social Research Center, University of Castilla La Mancha, Edificio Melchor Cano. Campus Universitario, s/n. 16071. Cuenca, Spain; Nursing Faculty, Edificio Melchor Cano, University of Castilla-La Mancha, Campus Universitario, s/n. 16071. Cuenca, Spain.
Ann Phys Rehabil Med. 2025 Mar;68(2):101890. doi: 10.1016/j.rehab.2024.101890. Epub 2024 Dec 12.
Chronic obstructive pulmonary disease (COPD) is characterized by a gradual deterioration of respiratory capacity, with worsening fatigue, weakness, activity intolerance, and dyspnea, influencing the person's emotional state and quality of life (QoL).
A network meta-analysis (NMA) was performed to determine the effects of different physical activity interventions on overall QoL in people with COPD, followed by a meta-analysis on the effect of these interventions on the different domains of the QoL scales.
A literature search was performed from inception to December 2023. Randomized controlled trials on the effectiveness of exercise programs on QoL in people with COPD were included. We assessed the risk of bias using the Cochrane Risk of Bias (RoB 2.0) tool and used the Grading of Recommendations, Assessment, Development, and Evaluation tool (GRADE) to assess the quality of the evidence. Pairwise meta-analysis and NMA for direct and indirect evidence were performed.
A total of 54 studies were included in the NMA. The largest effects were for active mind-body movement therapy (AMBMT) programs versus control interventions (usual practice) for total QoL (effect size [ES] 0.87; 95 % CI 0.65-1.09), followed by endurance (END) vs control (ES 0.75; 95 % CI 0.27-1.24) and combined (COMB) versus control (ES 0.73; 95 % CI 0.02-1.43). The results reflected an improvement in all subdomains of the QoL scales, except for social support.
AMBMT should be considered the most effective strategy to improve overall QoL in people with COPD, followed by END and COMB interventions. Physical activity interventions produce a positive effect in all the QoL domains studied, except for social support.
CRD42023393463.
慢性阻塞性肺疾病（COPD）的特征是呼吸能力逐渐下降，伴有疲劳、虚弱、活动不耐受和呼吸困难加重，影响患者的情绪状态和生活质量（QoL）。
进行一项网状Meta分析（NMA）以确定不同体育活动干预对COPD患者总体生活质量的影响，随后对这些干预对生活质量量表不同领域的影响进行Meta分析。
从研究开始至2023年12月进行文献检索。纳入关于运动计划对COPD患者生活质量有效性的随机对照试验。我们使用Cochrane偏倚风险（RoB 2.0）工具评估偏倚风险，并使用推荐分级、评估、制定和评价工具（GRADE）评估证据质量。进行直接和间接证据的成对Meta分析和NMA。
NMA共纳入54项研究。对于总体生活质量，积极的身心运动疗法（AMBMT）计划与对照干预（常规治疗）相比效果最大（效应量[ES] 0.87；95%CI 0.65 - 1.09），其次是耐力（END）与对照（ES 0.75；95%CI 0.27 - 1.24）以及综合（COMB）与对照（ES 0.73；95%CI 0.02 - 1.43）。结果反映了生活质量量表所有子领域的改善，但社会支持领域除外。
应将AMBMT视为改善COPD患者总体生活质量的最有效策略，其次是END和COMB干预。体育活动干预在除社会支持外的所有研究的生活质量领域均产生积极影响。
PROSPERO注册号：CRD42023393463。
