Zheng Baili, Cheng Yaling, Ma Lan, Cai Yvxuan, Li Yongchao, Liu Yingyu
College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi, China.
Xinjiang Key Laboratory of Herbivore Drug Research and Creation, Urumqi, China.
Foodborne Pathog Dis. 2024 Dec 12. doi: 10.1089/fpd.2024.0120.
Shiga toxin-producing (STEC) is a significant pathogen that can cause foodborne illnesses and pose a serious public health problem. To date, no systematic evaluation or meta-analysis of STEC carriage in Chinese cattle has been conducted. Therefore, we conducted a systematic review and meta-analysis to assess the prevalence of STEC in cattle in China over the past decade. We retrieved 1868 articles from 6 databases (PubMed, Web of Science, CNKI, Wanfang, VIP, and Baidu). Based on criteria such as sample source, isolation time, and species, we selected 39 studies (comprising 16,437 samples from 14 provinces) for systematic review and meta-analysis. The analysis results indicated that the pooled prevalence of in cattle during the selected time period was 6% (95% CI: 0.03-0.09). Subgroup analysis revealed variations in STEC positivity rates across different sectors. The highest positivity rate was observed in the slaughter and processing sector (12%, 95% CI: 0.03-0.17), followed by the retail sector (6%, 95% CI: 0.01-0.13), with the breeding sector showing the lowest rate (5%, 95% CI: 0.03-0.17). Among the regions studied, Shandong exhibited the highest pooled prevalence (15%, 95% CI: 0.01-0.30), followed by Hebei (12%, 95% CI: 0.00-0.30) and Hubei (11%, 95% CI: 0.03-0.09). These findings indicate an uneven distribution of STEC in cattle across China. Our systematic evaluation of data over the past decade provides insights into the prevalence of STEC in cattle in China. These findings may assist in the prevention and control of STEC in cattle in the country. We recommend conducting further epidemiological investigations and establishing comprehensive surveillance programs to identify risk factors associated with STEC in cattle, thereby enhancing prevention and control strategies.
产志贺毒素大肠杆菌（STEC）是一种重要的病原体，可引发食源性疾病并造成严重的公共卫生问题。迄今为止，尚未对中国牛群中STEC携带情况进行系统评估或荟萃分析。因此，我们进行了一项系统评价和荟萃分析，以评估过去十年中国牛群中STEC的流行情况。我们从6个数据库（PubMed、Web of Science、中国知网、万方、维普和百度）中检索到1868篇文章。基于样本来源、分离时间和物种等标准，我们选择了39项研究（包括来自14个省份的16437个样本）进行系统评价和荟萃分析。分析结果表明，在选定时间段内牛群中STEC的合并流行率为6%（95%置信区间：0.03 - 0.09）。亚组分析显示不同部门的STEC阳性率存在差异。屠宰和加工部门的阳性率最高（12%，95%置信区间：0.03 - 0.17），其次是零售部门（6%，95%置信区间：0.01 - 0.13），养殖部门的阳性率最低（5%，95%置信区间：0.03 - 0.17）。在所研究的地区中，山东的合并流行率最高（15%，95%置信区间：0.01 - 0.30），其次是河北（12%，95%置信区间：0.00 - 0.30）和湖北（11%，95%置信区间：0.03 - 0.09）。这些发现表明STEC在中国牛群中的分布不均衡。我们对过去十年数据的系统评估为了解中国牛群中STEC的流行情况提供了见解。这些发现可能有助于该国牛群中STEC的预防和控制。我们建议开展进一步的流行病学调查并建立全面的监测计划，以识别与牛群中STEC相关的风险因素，从而加强预防和控制策略。
