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Acute myeloid leukemia associated RUNX1 variants induce aberrant expression of transcription factor TCF4.

作者信息

Gerritsen Mylène, In 't Hout Florentien E M, Knops Ruth, Mandos Bas L R, Decker Melanie, Ripperger Tim, van der Reijden Bert A, Martens Joost H A, Jansen Joop H

机构信息

Department of Laboratory medicine, Laboratory of Hematology, Radboud University medical center, Nijmegen, The Netherlands.

Department of hematology, Radboud University medical center, Nijmegen, The Netherlands.

出版信息

Leukemia. 2025 Feb;39(2):520-523. doi: 10.1038/s41375-024-02470-w. Epub 2024 Dec 12.

DOI:10.1038/s41375-024-02470-w
PMID:39668235
Abstract
摘要

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Cancer Cell. 2022 Aug 8;40(8):850-864.e9. doi: 10.1016/j.ccell.2022.07.002. Epub 2022 Jul 21.
2
Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN.成人 AML 的诊断与治疗：ELN 专家组代表发布的 2022 年国际专家建议
Blood. 2022 Sep 22;140(12):1345-1377. doi: 10.1182/blood.2022016867.
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International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data.
国际髓系肿瘤和急性白血病分类：整合形态学、临床和基因组数据。
Blood. 2022 Sep 15;140(11):1200-1228. doi: 10.1182/blood.2022015850.
4
The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms.世界卫生组织血液淋巴肿瘤分类第五版：髓系和组织细胞/树突状肿瘤。
Leukemia. 2022 Jul;36(7):1703-1719. doi: 10.1038/s41375-022-01613-1. Epub 2022 Jun 22.
5
Validation and clinical application of transactivation assays for RUNX1 variant classification.用于RUNX1变异分类的反式激活分析的验证及临床应用
Blood Adv. 2022 Jun 14;6(11):3195-3200. doi: 10.1182/bloodadvances.2021006161.
6
Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies.伴有相关髓系恶性肿瘤的家族性血小板疾病中RUNX1变异体的功能分类
Leukemia. 2021 Nov;35(11):3304-3308. doi: 10.1038/s41375-021-01200-w. Epub 2021 Mar 10.
7
Transcription factor 4 () expression predicts clinical outcome in mutated and translocated acute myeloid leukemia.转录因子4（）表达可预测 突变型和易位型急性髓系白血病的临床结局。 （你提供的原文中“Transcription factor 4 ()”括号里内容缺失，请补充完整准确信息以便更精准翻译 ）
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Cancer Cell. 2016 Nov 14;30(5):764-778. doi: 10.1016/j.ccell.2016.10.002.
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Blood. 2013 Nov 21;122(22):3616-27; quiz 3699. doi: 10.1182/blood-2013-08-518886. Epub 2013 Sep 12.