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子宫腺肌病合并子宫脓肿形成经腺肌病切除术治疗:两例报告。

Adenomyosis with uterine abscess formation treated by adenomyomectomy: A report of two cases.

作者信息

Hiratsuka Daiki, Ishizawa Chihiro, Iida Rei, Fukui Yamato, Matsuo Mitsunori, Nishida Masato, Ikemura Masako, Harada Miyuki, Wada-Hiraike Osamu, Osuga Yutaka, Hirota Yasushi

机构信息

Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Department of Obstetrics and Gynecology, National Hospital Organization, Kasumigaura Medical Center, Kasumigaura, Japan.

出版信息

J Obstet Gynaecol Res. 2025 Jan;51(1):e16185. doi: 10.1111/jog.16185.

DOI:10.1111/jog.16185
PMID:39668455
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11638508/
Abstract

Uterine adenomyosis is a common disease in women of reproductive age that causes dysmenorrhea, abnormal uterine bleeding, infertility, and obstetric complications. Rarely, adenomyosis can lead to abscess formation, which is refractory to antibiotics and occasionally requires surgical treatment, such as hysterectomy. However, hysterectomy should be avoided in patients who seek to preserve fertility. Herein, for the first time, we report two cases of uterine adenomyosis with abscess formation during assisted reproductive procedures that were successfully treated with adenomyomectomy, thereby preserving fertility. A history of repeated intrauterine procedures and infections was crucial in making an appropriate preoperative diagnosis. Adenomyomectomy can be an effective treatment for adenomyosis associated with abscess in patients who wish to preserve fertility.

摘要

子宫腺肌病是育龄期女性的常见疾病,可导致痛经、异常子宫出血、不孕和产科并发症。罕见情况下,腺肌病可导致脓肿形成,对抗生素治疗无效,偶尔需要手术治疗,如子宫切除术。然而,对于有生育需求的患者应避免进行子宫切除术。在此,我们首次报告两例在辅助生殖过程中发生子宫腺肌病合并脓肿形成的病例,通过腺肌病切除术成功治疗,从而保留了生育能力。反复的宫腔操作和感染史对于做出准确的术前诊断至关重要。对于希望保留生育能力的腺肌病合并脓肿患者,腺肌病切除术可能是一种有效的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a68/11638508/9fa2f950a90f/JOG-51-0-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a68/11638508/b7ffb5210576/JOG-51-0-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a68/11638508/9fa2f950a90f/JOG-51-0-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a68/11638508/b7ffb5210576/JOG-51-0-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a68/11638508/9fa2f950a90f/JOG-51-0-g002.jpg

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Adenomyosis with uterine abscess formation treated by adenomyomectomy: A report of two cases.子宫腺肌病合并子宫脓肿形成经腺肌病切除术治疗:两例报告。
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Conservative surgery of diffuse adenomyosis with TOUA: Single surgeon experience of one hundred sixteen cases and report of fertility outcomes.经阴道超声引导下子宫腺肌病病灶切除术治疗弥漫型子宫腺肌病:单中心 116 例临床经验及生育结局报道。
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本文引用的文献

1
Pregnancy is associated with reduced progression of symptomatic adenomyosis: a retrospective pilot study.妊娠与症状性子宫腺肌病的进展减少相关:一项回顾性试点研究。
BMC Pregnancy Childbirth. 2023 Sep 4;23(1):634. doi: 10.1186/s12884-023-05956-0.
2
Rare complication of adenomyosis: acute purulent peritonitis and septicaemia in a young nulligravida.子宫腺肌病的罕见并发症:年轻初产妇急性化脓性腹膜炎并脓毒症。
BMJ Case Rep. 2021 Nov 29;14(11):e238374. doi: 10.1136/bcr-2020-238374.
3
Pregnancy and delivery outcomes in the women who have received adenomyomectomy: Performed by a single surgeon by a uniform surgical technique.
接受子宫腺肌瘤切除术的女性的妊娠和分娩结局:由同一位外科医生采用统一的手术技术进行。
Taiwan J Obstet Gynecol. 2021 Jan;60(1):99-102. doi: 10.1016/j.tjog.2020.11.015.
4
Inflammation calls for more: Severe pelvic inflammatory disease with or without endometriosis. Outcomes on 311 laparoscopically treated women.炎症需要更多关注:伴有或不伴有子宫内膜异位症的严重盆腔炎性疾病。311 例腹腔镜治疗女性的结局。
J Gynecol Obstet Hum Reprod. 2021 Mar;50(3):101811. doi: 10.1016/j.jogoh.2020.101811. Epub 2020 May 17.
5
Role of transvaginal sonography and magnetic resonance imaging in the diagnosis of uterine adenomyosis.经阴道超声和磁共振成像在子宫腺肌病诊断中的作用。
Fertil Steril. 2018 Mar;109(3):389-397. doi: 10.1016/j.fertnstert.2018.01.024.
6
Adenomyosis and adverse perinatal outcomes: increased risk of second trimester miscarriage, preeclampsia, and placental malposition.子宫腺肌病与不良围产期结局:孕中期流产、子痫前期和胎盘位置异常风险增加。
J Matern Fetal Neonatal Med. 2018 Feb;31(3):364-369. doi: 10.1080/14767058.2017.1285895. Epub 2017 Feb 9.
7
A rapidly growing adenomyosis associated with preterm delivery and postpartum abscess formation.一种与早产及产后脓肿形成相关的快速进展的子宫腺肌病。
Taiwan J Obstet Gynecol. 2016 Aug;55(4):620-2. doi: 10.1016/j.tjog.2015.02.008.
8
Microabscess within adenomyosis combined with sepsis.子宫腺肌病合并败血症时的微脓肿。
Kaohsiung J Med Sci. 2013 Jul;29(7):400-1. doi: 10.1016/j.kjms.2012.11.009. Epub 2013 Jan 18.
9
Sonographic and magnetic resonance imaging findings of pelvic abscess following uterine perforation sustained during office endometrial sampling.门诊子宫内膜取样时发生子宫穿孔后盆腔脓肿的超声及磁共振成像表现
J Clin Ultrasound. 2011 Jun;39(5):283-6. doi: 10.1002/jcu.20770. Epub 2010 Dec 28.
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Conservative surgical management for diffuse uterine adenomyosis.弥漫性子宫腺肌病的保守性手术治疗。
Fertil Steril. 2010 Jul;94(2):715-9. doi: 10.1016/j.fertnstert.2009.03.046. Epub 2009 May 5.