Weinreb H J
Arch Neurol. 1985 Jan;42(1):50-4. doi: 10.1001/archneur.1985.04060010056016.
Fingerprint dermatoglyphic patterns in 50 patients with presumed senile dementia of the Alzheimer type (SDAT) were compared with a control group of 50 patients with other neurologic diseases and with population norms. Patients with SDAT showed a significantly increased frequency of ulnar loops on their fingertips and a concomitantly decreased frequency of whorls and arches. A pattern of eight or more ulnar loops was found significantly more often in patients with SDAT (72%) than in the control group (26%). Fourteen patients with SDAT had ulnar loops on all ten fingers; this occurred in four patients in the control group. Radial loops on the fourth and fifth digits were more prevalent in patients with SDAT. The fingerprint patterns observed in patients with SDAT are congruent with patterns repeatedly found in Down's syndrome, and support the known associations between these two diseases at a further level.
对50例疑似阿尔茨海默型老年痴呆症（SDAT）患者的指纹皮纹模式与50例患有其他神经系统疾病的对照组患者以及人群标准进行了比较。SDAT患者指尖尺侧箕纹的出现频率显著增加，同时涡纹和弓纹的出现频率降低。SDAT患者中出现8个或更多尺侧箕纹的模式明显比对照组（26%）更常见（72%）。14例SDAT患者的10个手指均有尺侧箕纹；对照组中有4例出现这种情况。SDAT患者中，第四和第五指的桡侧箕纹更为普遍。在SDAT患者中观察到的指纹模式与在唐氏综合征中反复发现的模式一致，并在更深层次上支持了这两种疾病之间的已知关联。
