使用电休克疗法治疗双相情感障碍的经验：来自印度北部的一项回顾性研究。
Experience of using electroconvulsive therapy for bipolar disorder: A retrospective study from North India.
作者信息
Grover Sandeep, Sharma Namita, Chakrabarti Subho
机构信息
Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
Indian J Psychiatry. 2024 Oct;66(10):973-977. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_222_24. Epub 2024 Oct 17.
BACKGROUND
Little information is available on response to electroconvulsive therapy (ECT) in patients with bipolar disorder (BD) from India.
AIM
This exploratory study aims to evaluate and compare the sociodemographic and clinical profiles, treatment outcomes of BD patients with depression and mania/mixed episode who received ECT and to evaluate the predictors of response to ECT.
RESULTS
Data of 278 BD patients who received 325 ECT courses were extracted from the ECT register. The number courses of ECT for bipolar depression (n = 202) exceeded those for mania/mixed episodes (n = 123). In terms of response to ECT, >75% response was achieved in 63.3% cases and >50% response was seen in about 90% of the patients. No significant difference was seen in response to ECTs between bipolar depression and mania/mixed episodes.
CONCLUSION
The present study suggests that about two-thirds of the BD patients show more than 75% response to ECT, and more than 90% of the BD patients show more than 50% response to ECT.
背景
关于印度双相情感障碍（BD）患者对电休克治疗（ECT）的反应，可获取的信息较少。
目的
这项探索性研究旨在评估和比较接受ECT的双相情感障碍伴抑郁及躁狂/混合发作患者的社会人口统计学和临床特征、治疗结果，并评估ECT反应的预测因素。
结果
从ECT登记册中提取了278例接受325个ECT疗程的双相情感障碍患者的数据。双相抑郁（n = 202）的ECT疗程数超过躁狂/混合发作（n = 123）。在ECT反应方面，63.3%的病例实现了>75%的反应，约90%的患者有>50%的反应。双相抑郁和躁狂/混合发作对ECT的反应无显著差异。
结论
本研究表明，约三分之二的双相情感障碍患者对ECT有超过75%的反应，超过90%的双相情感障碍患者对ECT有超过50%的反应。
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