Valentim Flávia de Oliveira, Oliveira Cristiano Claudino, Miot Hélio Amante
Department of Dermatology, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu (SP), Brazil.
Department of Pathology, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu (SP), Brazil.
An Bras Dermatol. 2019 Jan-Feb;94(1):99-101. doi: 10.1590/abd1806-4841.20198513.
Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder is a rare disease, with an indolent evolution and benign course. The classic presentation is a solitary nodule on the face or trunk. The disorder's rarity and clinical and histopathological characteristics, can make the diagnosis difficult. We present the case of a 36-year-old Caucasian woman with a purplish erythematous nodule, hardened, shiny, asymptomatic, on the left nasal ala, which had grown progressively for 45 days. Histopathological examination and immunohistochemistry panel demonstrated alterations consistent with primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder. There was complete remission of the condition within 60 days of treatment with potent occlusive corticosteroids.
原发性皮肤CD4+小/中型T细胞淋巴增殖性疾病是一种罕见疾病，病程进展缓慢且呈良性。典型表现为面部或躯干上的单个结节。该疾病的罕见性以及临床和组织病理学特征可能导致诊断困难。我们报告一例36岁白种女性病例，其左侧鼻翼有一个紫色红斑结节，质地硬、有光泽、无症状，已持续渐进性生长45天。组织病理学检查和免疫组化结果显示符合原发性皮肤CD4+小/中型T细胞淋巴增殖性疾病改变。使用强效封闭性皮质类固醇治疗60天内病情完全缓解。
