Edward Stephen
Department of Mathematics and Statistics, University of Dodoma, Postal address: Box 338, Dodoma, Tanzania.
Heliyon. 2024 May 16;10(10):e31242. doi: 10.1016/j.heliyon.2024.e31242. eCollection 2024 May 30.
, a highly contagious bacterial infection causing diarrhea, fever, and abdominal pain, necessitates a deep understanding of its transmission dynamics to devise effective control measures. Our study takes a novel approach, employing a fractional order framework to explore the influence of memory and control measures on transmission dynamics, thereby making a unique contribution to the field. The model is presented as a system of Caputo fractional differential equations capturing time constant controls. The Caputo derivatives are chosen for their inherent benefits. The qualitative features of the model, such as the solutions' existence and uniqueness, positivity, and boundedness, are thoroughly investigated. Moreover, the equilibria of the model are derived and analyzed for their stability using suitable theorems. In particular, local stability was proved through Routh's criteria, while global stability results were established in the Ulam-Hyers sense. The model is then solved numerically with the help of the predict-evaluate-correct-evaluate method of Adams-Bashforth-Moulton. The numerical results underscore the significant impact of memory on disease evolution, highlighting the novelty of integrating memory-related aspects into the meticulous planning of effective disease control strategies. Using fractional-order derivatives is more beneficial for understanding the dynamics of transmission than integral-order models. The advantage of fractional derivatives is their ability to provide numerous degrees of freedom, allowing for a broader range of analysis of the system's dynamic behaviour, including nonlocal solutions. Also, an investigation on the impacts of control measures via parameter variation is done; the findings show that applying treatment and sanitation minimizes disease eruption.
是一种导致腹泻、发热和腹痛的高度传染性细菌感染,需要深入了解其传播动态以制定有效的控制措施。我们的研究采用了一种新颖的方法,运用分数阶框架来探索记忆和控制措施对传播动态的影响,从而为该领域做出独特贡献。该模型以捕获时间常数控制的卡普托分数阶微分方程组形式呈现。选择卡普托导数是因其固有的优点。对模型的定性特征,如解的存在性和唯一性、正性和有界性进行了深入研究。此外,推导了模型的平衡点,并使用合适的定理对其稳定性进行了分析。特别是,通过劳斯判据证明了局部稳定性,而在乌拉姆 - 海尔斯意义下建立了全局稳定性结果。然后借助亚当斯 - 巴什福思 - 莫尔顿的预测 - 评估 - 校正 - 评估方法对模型进行数值求解。数值结果强调了记忆对疾病演变的重大影响,突出了将与记忆相关的方面纳入有效疾病控制策略的精心规划中的新颖性。使用分数阶导数比整数阶模型更有利于理解传播动态。分数阶导数的优势在于它们能够提供众多自由度,允许对系统的动态行为进行更广泛的分析,包括非局部解。此外,通过参数变化对控制措施的影响进行了研究;结果表明应用治疗和卫生措施可使疾病爆发最小化。